Table 1 Characteristics and outcomes of the study patients (N = 137)
Variables | Median (interquartile range) unless stated otherwise |
|---|---|
Age, years | 53 (43–69) |
Male, no. (%) | 97 (70.8) |
Comorbidities, no. (%): | |
- Diabetes mellitus | 41 (30) |
- Cancer | 28 (20) |
- Chronic lung disease | 33 (24) |
- Congestive heart failure | 56 (41) |
Baseline organ support therapy, no. (%): | |
- Inotropes | 54 (39) |
- Mechanical ventilation | 68 (50) |
- Intra-aortic balloon pump | 2 (2) |
Baseline physical signs, no. (%): | |
- Tachycardia (> 110 bpm) | 68 (50) |
- Hypotension (< 100 mmHg) | 70 (51) |
- Tachypnoea (> 30 breaths/min) | 77 (56) |
- Hypothermia (< 36C°) | 19 (14) |
- Altered mental state | 38 (28) |
- Hypoxaemia (SaO2 < 90%) | 104 (76) |
Haemoglobin concentrations, d/L | 110 (89–131) |
Haematocrit, % | 33 (27–40) |
Plasma creatinine conc., μmol/L | 89 (64–137) |
CIN risk score | 9 (4–16) |
Pulmonary Embolism Severity Index | 144 (99–190) |
APACHE II score | 23 (17–31) |
Outcomes: | |
Maximum creatinine conc. within 48 h after CTPA, μmol/L | 92 (65–178) |
CIN within 48 h of CTPA, no. (%) | 56 (41) |
Required subsequent dialysis, no. (%) | 35 (26) |
Acute pulmonary embolism (PE), no. (%) | 21 (15) |
Bilateral PE, no. (%) | 14 (10) |
Pneumonia on CTPA, no. (%) | 66 (48) |
Hospital mortality, no. (%) | 69 (50) |
Length of ICU stay, days | 6 (3–16) |
Length of hospital stay, days | 13 (7–26) |
CIN prediction score > 10: PPV for CIN, % | 75.5 |
CIN prediction score > 10: NPV for CIN, % | 86.6 |
CIN prediction score > 12: PPV for dialysis, % | 58.2 |
CIN prediction score > 12: NPV for dialysis, % | 94.0 |