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Table 1 Clinical definitions of sepsis used in the study

From: The impact of sepsis, delirium, and psychological distress on self-rated cognitive function in ICU survivors—a prospective cohort study

Systemic inflammatory response syndrome (SIRS) Two or more of the following:
 • Temperature > 38 or < 36 °C
 • Heart rate > 90/min
 • Respiratory rate > 20/min
 • White blood cell count > 12 × 109 or < 4 × 109
Sepsis SIRS and evidence of infection
Severe sepsis At least one sign of sepsis-associated organ dysfunction, hypoperfusion or hypotension, including lactate acidosis, oliguria, or acute alteration of mental state
Septic shock Severe sepsis with hypotension (systolic blood pressure < 90 mmHg or a reduction from baseline > 40 mmHg) refractory to adequate fluid resuscitations or need of inotropic drug