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Table 2 The summary of the newly added findings on the management of pediatric sepsis

From: Update on pediatric sepsis: a review

# Administer the first appropriate antimicrobials within 3 h after the recognition
# Lactate clearance might be promising for children with elevated lactate level
# Transthoracic echocardiography should be encouraged to use for the evaluation of the hemodynamics and treatment response
# Dynamic variables would be more preferable to static variables to evaluate fluid responsiveness, but the only reliable parameter is respiratory variation in aortic blood flow peak velocity (ΔVpeak) measured with echocardiography so far
# Adrenaline would be more preferable to dopamine for the first line catecholamine in children with fluid-refractory septic shock
# Serial meticulous evaluation of the hemodynamics and adjustment of the management are essential
# Be more cautious about the use of vasopressin/terlipressin for children with fluid-refractory septic shock
# Be more “conservative” than ever about the administration of corticosteroids