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Table 2 Baseline characteristics of patients with either severe sepsis or septic shock treated in the ED with our bundled care initiative

From: Unexpected intensive care transfer of admitted patients with severe sepsis

  ED directly to ICU ED towards (including delayed ICU transfers within 48 h) p value
Number 556 358  
Age, years 58.8 (±18) 58.4 (±18) 0.785
Sex, %male (n) 57.6% (320) 55.3% (198) 0.337
Triage SBP (mm Hg) 105 (±28) 112 (±28) 0.001
Shock index (SBP/HR) 1.11 (±0.33) 1.02 (±0.30) 0.002
Triage HR (BPM) 111 (±29) 110 (±23) 0.662
Fluids per kg within 6 h of presentation 40.1 (±20.7) 33.2 (±18.9) <0.005
Initial lactate (mmol/L) 4.1 ± 3.4 2.8 ± 2.3 <0.005
% with septic shock at presentation (n) 55.6% (310) 0% (0) <0.005
Site of infection%, (n)    <0.005
 Abdominal 14.9% (83) 17.6% (63)  
 Cardiac 1.3% (7) 1.1% (4)  
 Central nervous system 1.1% (6) 1.4% (5)  
 Genitourinary 21.9% (122) 31.3% (112)  
 Musculoskeletal 7.0% (39) 13.4% (48)  
 Pulmonary 24.8% (138) 22.3% (80)  
 Unknown/othersa 28.9% (161) 12.9% (46)  
Mortality,% (n) 24.6% (137) 12.0% (43) <0.005
  1. aOthers include patients with multiple organ system infections, catheter-related infections, head and neck infection, and neutropenic fever without definitive source