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Table 3 Logistic regression analyses of the coagulation/fibrinolysis markers for 28-day mortality

From: Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis

  Univariate analyses Multivariate analyses
Markers OR 95% CI P value OR 95% CI P value
CRP (mg/dl) 1.020 0.986–1.054 NS    
PCT (ng/ml) 1.000 0.993–1.003 NS    
PSEP (pg/ml) 1.000 1.000–1.000 <0.05 1.000 0.999–1.000 NS
Platelet count (×104/μl) 1.003 0.973–1.028 NS    
PT-INR 0.993 0.834–1.034 NS    
APTT (s) 1.013 0.992–1.033 NS    
AT (%) 0.983 0.966–1.000 NS    
D-dimer (μg/ml) 1.005 0.995–1.015 NS    
TAT (ng/ml) 1.015 1.003–1.027 <0.05 0.999 0.982–1.014 NS
PIC (μg/ml) 1.021 0.940–1.094 NS    
PC (%) 0.977 0.959–0.993 <0.01 0.986 0.967–1.004 NS
TM (U/ml) 1.005 0.996–1.014 NS    
SF (μg/ml) 1.021 1.008–1.034 <0.01 1.014 0.997–1.031 NS
PAI-1 (ng/ml) 1.002 1.001–1.003 <0.01 1.002 1.000–1.003 <0.05
SOFA score 1.200 1.078–1.348 <0.01 1.075 0.943–1.231 NS
  1. OR odds ratio, CI confidence interval, CRP C-reactive protein, PCT procalcitonin, PSEP presepsin, PT-INR prothrombin time-international normalized ratio, APTT activated partial thromboplastin time, AT antithrombin, TAT thrombin-antithrombin complex, PIC plasmin α2-plasmin inhibitor complex, PC protein C, TM thrombomodulin, SF soluble fibrin, PAI-1 plasminogen activator inhibitor-1, SOFA sequential organ failure assessment