Skip to main content

Table 1 Comparison of patient characteristics

From: Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis

  Total
n = 186
Non-survivors
n = 36
Survivors
n = 150
P value
Age (years old) 72 (62–79) 76 (68–81) 71 (61–78) <0.05
Male 115 (62) 20 (56) 95 (63) 0.39
Infection focus     <0.05
 Lung 77 (41) 8 (22) 69 (46)  
 Abdomen 61 (33) 21 (58) 40 (27)  
 Skin and soft tissue 13 (7) 3 (8) 10 (7)  
 Urinary tract 11 (6) 2 (6) 9 (6)  
 Others 11 (6) 1 (3) 10 (7)  
 Unknown 13 (7) 1 (3) 12 (8)  
 Mean blood pressure (mmHg) 78 (67–97) 74 (63–92) 79 (67–97) 0.13
 Heart rate (bpm) 110 (95–120) 111 (95–120) 110 (95–121) 0.77
 Respiratory rate (bpm) 23 (19–28) 24 (20–28) 22 (18–28) 0.28
 Body temperature (°C) 36.9 (36.3-37.9) 36.7 (36.0-37.4) 36.9 (36.4-38.1) 0.06
JAAM DIC score 3 (2–5) 4 (2–6) 3 (2–5) 0.13
JAAM DIC positive rate 87 (47) 21 (58) 66 (44) 0.12
SOFA score 8 (5–11) 11 (8–13) 8 (5–11) <0.01
 Respiratory 2 (2–3) 2 (1–3) 2 (2–3) 0.87
 Cardiovascular 1 (0–4) 4 (0–4) 1 (0–4) <0.01
 Liver 0 (0–1) 0 (0–1) 0 (0–1) 0.95
 Renal 1 (0–3) 3 (1–4) 1 (0–3) <0.01
 Coagulation 1 (0–2) 0 (0–2) 1 (0–2) 0.85
 CNS 1 (0–2) 1 (0–3) 1 (0–2) 0.95
rhs TM 46 (25) 11 (31) 35 (23) 0.37
AT III 28 (15) 6 (17) 22 (15) 0.76
IVIG 92 (49) 21 (58) 71 (47) 0.24
CRRT 44 (24) 17 (47) 27 (18) <0.01
PMX-DHP 28 (15) 9 (25) 19 (13) 0.06
  1. Data are presented as median (interquartile range) or number (percentage)
  2. JAAM Japanese Association for Acute Medicine, DIC disseminated intravascular coagulation, SOFA sequential organ failure assessment, CNS central nervous system, rhs TM recombinant human soluble thrombomodulin, AT antithrombin, IVIG intravenous immunoglobulin, CRRT continuous renal replacement therapy, PMX-DHP direct hemoperfusion with polymyxin B-immobilized fiber