Skip to main content

Advertisement

Table 1 Baseline characteristics and outcomes of the study sample

From: Association between rapid serum sodium correction and rhabdomyolysis in water intoxication: a retrospective cohort study

  Overall Rhabdomyolysis (+) Rhabdomyolysis (−) p value
(n = 56) (n = 35) (n = 21)
Age, years 53.0 [42.0, 62.0] 47.0 [41.0, 59.5] 58.0 [47.0, 63.0] 0.056
Male sex 26 (46.4) 21 (60.0) 5 (23.8) 0.013
Underlying mental disorder 51 (91.1) 31 (88.6) 20 (95.2) 0.64
Convulsion 34 (60.7) 25 (71.4) 9 (42.9) 0.049
Lying down for >8 h before admission 43 (76.8) 30 (85.7) 13 (61.9) 0.054
Serum CK level on admission, IU/L 450 [194, 775] 661 [308, 944] 215 [78, 404] <0.001
Serum creatinine level on admission, mg/dL 0.60 [0.50, 0.70] 0.60 [0.50, 0.70] 0.50 [0.50, 0.70] 0.75
Serum sodium level on admission, mEq/L 110.5 [108.0, 113.3] 110.0 [108.0, 112.5] 111.0 [109.0, 116.0] 0.13
Serum sodium correction rate during first 12 h, mEq/L/h 1.15 [0.74, 1.31] 1.22 [1.11, 1.39] 0.71 [0.61, 0.85] <0.001
Serum sodium correction rate during first 24 h, mEq/L/h 1.02 [0.63, 1.20] 1.11 [0.97, 1.27] 0.60 [0.50, 0.74] <0.001
Serum sodium correction rate during first 48 h, mEq/L/h 0.58 [0.54, 0.61] 0.58 [0.56, 0.62] 0.57 [0.51, 0.61] 0.19
Muscle pain 4 (7.1) 4 (11.4) 0 (0.0) 0.29
Peak serum CK, IU/L 5249 [822, 21,003] 10,323 [5775, 35,695] 540 [236, 873] <0.001
Peak serum creatinine, mg/dL 0.70 [0.60, 0.80] 0.70 [0.60, 0.80] 0.60 [0.50, 0.70] 0.14
Hospital stay, days 9.0 [6.0, 11.0] 11.0 [8.5, 12.5] 5.0 [4.0, 8.0] <0.001
Acute kidney injury     0.012
 Stage 1 8 (14.3) 8 (22.9) 0 (0.0)  
 Stage 2 1 (1.8) 1 (2.9) 0 (0.0)  
 Stage 3 0 (0.0) 0 (0.0) 0 (0.0)  
 Osmotic demyelination syndrome 0 (0.0) 0 (0.0) 0 (0.0) NA
 Death 0 (0.0) 0 (0.0) 0 (0.0) NA
  1. Continuous variables are presented as median [interquartile range]. Categorical variables are presented as counts (percentage)
  2. CK creatine kinase, NA not applicable