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Table 6 Subgroup analysis: hemodynamic and respiratory parameters before and after high-flow nasal cannula therapy for serial circulation group (n = 13) and single ventricle group (n = 7)

From: Physiological impact of high-flow nasal cannula therapy on postextubation acute respiratory failure after pediatric cardiac surgery: a prospective observational study

  Serial circulation group (n = 13) Single ventricle group (n = 7)
Parameters Pre-HFNC Post-HFNC p value Pre-HFNC Post-HFNC p value
RR (breaths per minute) 43 (31.5–55) 25 (20.5–35.5) 0.003 44 (32–55) 34 (32–43) 0.2
PaCO2 (mmHg) 45.7 (41.1–53.2) 46.3 (42.7–48.2) 0.2 50.4 (38.1–61) 45.6 (38.6–57.7) 0.3
SaO2 (%) 95.4 (92.2–98.9) 98.7 (86.5–99.4) 0.5 69.3 (58.1–88.6) 80.6 (65.3–88.3) 0.2
SBP (mmHg) 95 (77–105) 76 (68.5–80) 0.007 85 (80–93) 80 (71–91) 0.3
HR (beats per minute) 150 (110–164) 115 (108–130) 0.08 138 (112–147) 143 (116–150) 0.4
Lactate (mmol/l) 1.1 (0.5–1.6) 0.9 (0.7–1.4) 0.4 1.1 (1.0–2.9) 1.1 (1.0–2.2) 0.5
  1. HFNC high-flow nasal cannula, RR respiratory rate, PaCO 2 partial pressure of arterial carbon dioxide, SaO 2 arterial oxygen saturation, SBP systolic blood pressure, HR heart rate