Table 6 Subgroup analysis: hemodynamic and respiratory parameters before and after high-flow nasal cannula therapy for serial circulation group (n = 13) and single ventricle group (n = 7)

RR (breaths per minute)

43 (31.5–55)

25 (20.5–35.5)

0.003

44 (32–55)

34 (32–43)

0.2

PaCO₂ (mmHg)

45.7 (41.1–53.2)

46.3 (42.7–48.2)

0.2

50.4 (38.1–61)

45.6 (38.6–57.7)

0.3

SaO₂ (%)

95.4 (92.2–98.9)

98.7 (86.5–99.4)

0.5

69.3 (58.1–88.6)

80.6 (65.3–88.3)

0.2

SBP (mmHg)

95 (77–105)

76 (68.5–80)

0.007

85 (80–93)

80 (71–91)

0.3

HR (beats per minute)

150 (110–164)

115 (108–130)

0.08

138 (112–147)

143 (116–150)

0.4

Lactate (mmol/l)

1.1 (0.5–1.6)

0.9 (0.7–1.4)

0.4

1.1 (1.0–2.9)

1.1 (1.0–2.2)

0.5