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Table 2 Hazard ratios for in-ICU AKI existence, in relation to mortality

From: Association between recurrence of acute kidney injury and mortality in intensive care unit patients with severe sepsis

 

Vital status (intra-hospital)

Vital status (90-day)

Vital status (end of follow-up)

Survival (N)

Death (N)

HR

(95% CI)

Survival (N)

Death (N)

HR

(95% CI)

Survival (N)

Death (N)

HR

(95% CI)

Including patients without AKI (N = 400)

298

102

   

290

110

   

212

188

   

 No AKI (n = 69)

62

7

1

 

61

8

1

 

47

22

1

 

 AKI = 1 (n = 252)

192

60

1.68a

0.74

3.82

188

64

1.54a

0.71

3.34

139

113

1.00a

0.61

1.63

 AKI ≥2 (n = 79)

44

35

2.73a

1.15

6.51

41

38

2.57a

1.13

5.83

26

53

1.61a

0.93

2.77

Linear p trend

  

0.006

    

0.005

    

0.021

  

Excluding patients without AKI (N = 331)

236

95

   

229

102

   

165

166

   

 AKI = 1 (n = 252)

192

60

1

 

188

64

1

 

139

113

1

 

 AKI ≥2 (n = 79)

44

35

2.48b

1.47

4.19

41

38

2.54b

1.55

4.16

26

53

1.97b

1.36

2.84

  1. aHR = hazard ratio adjusted for sex, age, mechanical ventilation necessity, APACHE score, and baseline estimated glomerular filtration rate (GFR)
  2. bHR = hazard ratio adjusted for sex, age, mechanical ventilation necessity, APACHE score, baseline estimated GFR, complete recovery and KDIGO stage