| |
Unadjusted HR (95%-CI)
|
p
|
Adjusted HR (95%-CI)
|
p
|
|---|
|
CT-proET-1 > 74 pmol/L
|
2.731 (1.535–4.858)
|
0.001
|
2.193 (1.209–3.975)
|
0.01
|
|
Creatinine (per mg/dL)
|
1.034 (0.946–1.129)
|
0.461
|
–
|
n.s.
|
|
CRP (per mg/L)
|
1.002 (0.999–1.006)
|
0.129
|
–
|
n.s.
|
|
Bilirubin (per mg/dL)
|
1.16 (0.935–1.16)
|
0.176
|
–
|
n.s.
|
|
Prothrombin time (per %)
|
0.99 (0.979–1)
|
0.052
|
–
|
n.s.
|
|
Lactate (per mmol/L)
|
1.082 (0.949–1.234)
|
0.239
|
–
|
n.s.
|
|
Age (per year)
|
1.036 (1.014–1.059)
|
<0.001
|
1.028 (1.005–1.051)
|
0.04
|
- Variables with a univariate p < 0.25 were included in the multivariate model
-
Abbreviations: 95%-CI 95% confidence-interval, CRP C-reactive protein, CT-proET-1 C-terminal proendothelin-1, n.s. not significant
