|
Unadjusted HR (95%-CI)
|
p
|
Adjusted HR (95%-CI)
|
p
|
---|
CT-proET-1 > 74 pmol/L
|
2.658 (1.375–5.137)
|
0.004
|
2.663 (1.296–5.470)
|
0.008
|
Creatinine (per mg/dL)
|
–
|
n.s.
| | |
CRP (per mg/L)
|
–
|
n.s.
| | |
Bilirubin (per mg/dL)
|
1.129 (1.021–1.249)
|
0.018
|
–
|
n.s.
|
Prothrombin time (per %)
|
0.988 (0.977–1)
|
0.045
|
–
|
n.s.
|
Lactate (per mmol/L)
|
1.115 (1.03–1.207)
|
0.007
|
1.20 (1.109–1.298)
|
<0.001
|
Age (per year)
|
1.034 (1.011–1.058)
|
0.003
|
1.045 (1.019–1.71)
|
0.003
|
- Variables with an univariate p < 0.25 were included in the multivariate model
-
Abbreviations: 95%-CI, 95% confidence interval, CRP C-reactive protein, CT-proET-1 C-terminal proendothelin-1, n.s. not significant