Prolonged direct hemoperfusion using a polymyxin B immobilized fiber cartridge provides sustained circulatory stabilization in patients with septic shock: a retrospective observational before-after study

Table 3 Secondary outcomes

	PMX-DHP-2 h (n = 18)	PMX-DHP-12 h (n = 18)	P value
ICU-free days at day 28, days, median [IQR]	7 (0–23)	18 (0–24)	0.31
Vasopressor-free days at day 28, days, median [IQR]	5 [0–23]	21 [0–24]	0.11
RRT-free days at day 28, days, median [IQR]	2 [0–28]	20 [0–28]	0.31
Ventilator-free days at day 28, days, median [IQR]	3 (0–22)	18 (0–25)	0.22
ICU mortality, number (%)	7 (39%)	3 (17%)	0.26
Hospital mortality, number (%)	8 (44%)	8 (44%)	1.00

PMX-DHP-2 h polymyxin direct hemoperfusion for 2 h, PMX-DHP-12 h polymyxin direct hemoperfusion for 12 h, ICU intensive care unit, RRT renal replacement therapy, IQR interquartile range

ISSN: 2052-0492