Skip to main content

Table 2 The time course of the vasopressor dependency index, the mean blood pressure, and inotropic score within 12 h after starting the first PMX-DHP session

From: Prolonged direct hemoperfusion using a polymyxin B immobilized fiber cartridge provides sustained circulatory stabilization in patients with septic shock: a retrospective observational before-after study

 

0 h (baseline)

2 h

5 h

8 h

12 h

Vasopressor dependency index, mean ± SD

 PMX-DHP-2 h (n = 18)

0.52 ± 0.29

0.46 ± 0.28

0.37 ± 0.24

0.41 ± 0.28

0.39 ± 0.25

 PMX-DHP-12 h (n = 18)

0.50 ± 0.26

0.43 ± 0.20

0.36 ± 0.21

0.32 ± 0.22*

0.28 ± 018*

Mean blood pressure, mmHg, mean ± SD

 PMX-DHP-2 h (n = 18)

68.4 ± 8.9

76.9 ± 14.8

83.4 ± 14.2*

75.6 ± 14.9

78.2 ± 16.9

 PMX-DHP-12 h (n = 18)

70.3 ± 15.7

80.7 ± 13.8

86.4 ± 15.6*

87.0 ± 18.4*

87.7 ± 16.9*

Inotropic score, mean ± SD

 PMX-DHP-2 h (n = 18)

33.9 ± 17.3

33.3 ± 18.0

28.4 ± 14.8

27.4 ± 15.1

27.3 ± 15.4

 PMX-DHP-12 h (n = 18)

33.8 ± 14.8

34.6 ± 15.9

29.9 ± 14.1

24.7 ± 13.8

23.1 ± 13.1

  1. *P < 0.05 (Dunnett’s test with the reference value being the 0 h value)