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Table 2 Cytokine, chemokine, and growth factor removal 24 h after Cytosorb® treatment

From: Effect of extracorporeal cytokine removal on vascular barrier function in a septic shock patient

Parameter

Pre

Post

Rel. reduction (%)

 

Cytokine removal (pg/mL)

 

IL-1a

643.9

76

−88.2

IL-6

89.9

14.0

−84.4

CXCL8 (IL-8)

68.4

19.9

−70.9

IL-9

12.9

7.2

−44.2

IL-10

80.7

40.0

−49.6

IL-13

7.1

10.8

+51.5

FGF

48.1

21.4

−55.6

GM-CSF

57.5

38.6

−32.9

CXCL10 (IP-10)

24,723.7

2827.5

−88.6

CCL2 (MCP-1)

375.0

45.9

−87.8

CCL4 (MIP-1b)

125.4

39.2

−68.8

PDGF-bb

719.8

245.3

−65.9

RANTES

3912.2

1326.1

−66.1

TNF-a

59.2

24.8

−58.1

VEGF

63.7

19.5

−69.5

  1. IL interleukin, CXCL C-X-C motif chemokine, FGF fibroblast growth factor, GM-CSF granulocyte-macrophage colony-stimulating factor, IP interferon gamma produced protein, CCL C-C motif ligand, MIP macrophage inflammatory proteins, MCP monocyte chemotactic protein, PDGF platelet-derived growth factor, RANTES regulated on activation, normal T cell expressed and secreted, TNF tumor necrosis factor, VEGF vascular endothelial growth factor