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Table 2 Currently recommended management for trauma-induced coagulopathy (cited from [24] with modification)

From: Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview

Initial assessment and management
 Extent of traumatic hemorrhage assessed
 Patient in shock with identified source of bleeding treated immediately
 Patient in shock with unidentified source of bleeding sent for further investigation
 Coagulation, hematocrit, serum lactate, base deficit assessed
 Antifibrinolytic therapy (tranexamic acid within 3 h after injury) initiated
 Patient history of anticoagulant therapy assessed
 Systolic blood pressure of 80–90 mmHg achieved in absence of traumatic brain injury
 Measures to achieve normothermia implemented
 Target hemoglobin level 7–9 g/dl achieved
Surgical intervention
 Damage control surgery performed in hemodynamically unstable patient
Coagulation management
 Massive transfusion protocol with high plasma: red blood cell ratio employed
 Target fibrinogen level 1.5–2 g/l achieved
 Target platelet level achieved
 Prothrombin complex concentrate administered if indicated due to vitamin K antagonist, oral anticoagulant or evidence from viscoelastic monitoring