| |
All
|
Responders
|
Non-responders
| |
|---|
|
n = 33
|
n = 10
|
n = 23
|
p
|
|---|
|
Age
|
60.0 (13.6)
|
58.4 (16.2)
|
60.7 (12.7)
|
0.70
|
|
Sex
|
|
Male
|
15 (45 %)
|
4 (40 %)
|
11 (48 %)
|
0.97
|
|
Female
|
18 (55 %)
|
6 (60 %)
|
12 (52 %)
| |
|
Weight (kg)
|
72.1 (12.9)
|
75.0 (14.1)
|
70.9 (12.4)
|
0.44
|
|
APACHE II score
|
19.9 (6.9)
|
19.0 (5.8)
|
20.4 (7.5)
|
0.58
|
|
Died in hospital
|
|
Yes
|
16 (48 %)
|
7 (70 %)
|
9 (39 %)
|
0.21
|
|
No
|
17 (52 %)
|
3 (30 %)
|
14 (61 %)
| |
|
Admission to PLR (h)
|
26 [18, 52]
|
38 [21,102]
|
26 [16, 42]
|
0.25
|
|
Arrhythmia
|
|
Present
|
3/32 (9 %)
|
1/9 (11 %)
|
2/23 (9 %)
|
1.00
|
|
Absent
|
29/32 (91 %)
|
8/9 (89 %)
|
21/23 (91 %)
| |
|
Tidal volume (ml)
|
510 [463, 563]
|
540 [473, 660]
|
491 [460, 549]
|
0.39
|
|
Plateau pressure (cmH2O)
|
26.6 (7.1)
|
26.4 (5.5)
|
26.7 (7.7)
|
0.90
|
|
PEEP (cmH2O)
|
8.5 (2.5)
|
8.9 (2.8)
|
8.4 (2.4)
|
0.60
|
|
Respiratory rate (/min)
|
16.8 (4.2)
|
15.5 (2.4)
|
17.3 (4.7)
|
0.15
|
|
Spontaneous breathing
|
|
Yes
|
6/30 (20 %)
|
2/9 (22 %)
|
4/21 (19 %)
|
1.00
|
|
No
|
24/30 (80 %)
|
7/9 (78 %)
|
17/21 (81 %)
| |
|
Arterial line site:
|
|
Femoral
|
4 (12 %)
|
1 (10 %)
|
3 (13 %)
|
1.00
|
|
Other (radial and brachial)
|
29 (88 %)
|
9 (90 %)
|
20 (87 %)
| |
|
Diagnostic groups:
|
|
Septic shock
|
27 (82 %)
|
7 (70 %)
|
20 (87 %)
|
0.34
|
|
– Endocarditis
|
1 (3 %)
|
0 (0 %)
|
1 (4 %)
|
–
|
|
– Occult
|
7 (21 %)
|
2 (20 %)
|
5 (22 %)
|
–
|
|
– Peritonitis
|
8 (24 %)
|
2 (20 %)
|
6 (26 %)
|
–
|
|
– Pneumonia
|
11 (33 %)
|
3 (30 %)
|
8 (35 %)
|
–
|
|
SIRS
|
6 (18 %)
|
3 (30 %)
|
3 (13 %)
|
–
|
|
– Ischaemic bowel
|
2 (6 %)
|
1 (10 %)
|
1 (4 %)
|
–
|
|
– Occult
|
1 (3 %)
|
0
|
1 (4 %)
|
–
|
|
– Pancreatico-duodenectomy
|
1 (3 %)
|
0
|
1 (4 %)
|
–
|
|
– Pancreatitis
|
2 (6 %)
|
2 (20 %)
|
0
|
–
|
- Data are shown as mean (standard deviation), median (inter-quartile range), or number (percentage) with p value comparing responders to non-responders for certain characteristics. Sample sizes are as in column headings unless stated (some variables had small numbers of missing values)
