Skip to main content

Advertisement

Table 1 Demographic and laboratory data

From: Augmented renal clearance in Japanese intensive care unit patients: a prospective study

Variable All patients (n = 111) Patients with ARC (n = 43) Patients without ARC (n = 68) p valuea
Age, median (IQR) 67 (53–77) 55 (38–65) 72 (66–79) <0.05
Male sex, n (%) 62 (55.9) 22 (51.2) 40 (58.8) 0.44
Body weight (kg), median (IQR) 56.3 (49.9–68.2) 60.7 (52.8–74.1) 53.2 (47.9–62.5) <0.05
Body height (m), mean (SD) 1.61 (0.1) 1.64 (0.1) 1.59 (0.09) <0.05
Body mass index (kg/m2), mean (SD) 22.7 (3.88) 23.6 (3.75) 22.1 (3.87) <0.05
Body surface area (m2), median (IQR) 1.57 (1.46–1.79) 1.67 (1.54–1.85) 1.55 (1.41–1.69) <0.05
Diabetes mellitus, n (%) 22 (19.8) 5 (11.6) 17 (25) 0.09
Mechanical ventilation, n (%) 21 (18.9) 6 (14) 15 (22.4) 0.33
Vasopressor, n (%) 2 (1.8) 0 2 (2.9) 0.52
Inotrope, n (%) 8 (7.2) 2 (4.6) 6 (8.8) 0.48
Diuretic therapy, n (%) 6 (5.4) 1 (2.3) 5 (7.4) 0.4
APACHE II scores, median (IQR) 14 (10.5–19.5) 13 (8.5–15.5) 16 (11.8–23) <0.05
SOFA scores, median (IQR) 3 (2–5) 3 (2–4) 3 (2–5) 0.33
The cumulative number of SIRS, median (IQR) 1 (1–2) 1 (1–2) 1 (1–2) 0.96
Admission category, n (%)     
 Sepsisb 3 (2.7) 0 3 (4.4) 0.28
 Post-operative patients without sepsis 25 (22.5) 4 (9.3) 21 (30.9) <0.05
 Trauma 32 (28.8) 20 (46.5) 12 (17.6) <0.05
 ISS ≥ 16 19 10 9  
 ISS < 16 13 10 3  
 Others 51 (45.9) 19 (44.2) 32 (47.1) 0.85
Serum albumin (g/dL), median (IQR) 3.9 (3.4–4.3) 4.2 (3.7–4.4) 3.8 (3.2–4.2) <0.05
Blood glucose (mg/dL), median (IQR) 136 (115–160) 128 (111–150) 141 (118–168) 0.12
Mean urine output (mL/kg/h), median (IQR) 0.92 (0.64–1.36) 0.94 (0.7–1.4) 0.77 (0.6–1.35) 0.29
Fluid balance (mL), median (IQR) 739 (55.5–1290) 993 (−70–1460) 572 (81.3–1125) 0.33
  1. ARC augmented renal clearance, IQR interquartile range, SD standard deviation, APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, SIRS systemic inflammatory response syndrome, ISS injury severity score
  2. aThe p values were evaluated by comparison between patients with and without ARC
  3. bSepsis was diagnosed based on evidence of infection along with the presence of SIRS