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Table 2 Adverse events during early mobilization

From: Early mobilization of mechanically ventilated patients in the intensive care unit

Reference # n Early mobilization intervention Incidence of adverse events Adverse events
[24] 103 Active mobilization: 1449 sessions: sitting on bed and in chair, ambulation 0.96 % Fall, systolic blood pressure <90 mmHg, oxygen desaturation, feeding tube extraction, systolic blood pressure >200 mmHg
[3] 90 Passive and active therapy, bicycle ergometer exercise 3.76 % SpO2 < 90 %, systolic blood pressure >180 mmHg, >20 % decrease in diastolic blood pressure
[2] 104 Passive and active range of motion, sitting, balance exercises, activities of daily living, transfer training, walking 4.0 % Patient instability (most often because of perceived patient-ventilator asynchrony), 0.2 % serious (desaturation <80 %)
[29] 99 Active mobilization: 498 sessions 16 % Desaturation 5 %, heart rate increase >20 %, ventilator asynchrony/tachypnea, agitation/discomfort, device removal
[25] 20 Active mobilization: 424 sessions: chair sitting, head up tilt, walking 3 % Decreased muscle tone, hypoxemia, extubation, orthostatic, hypotension
[4] 150 Walking in place, sit to stand transfers, arm and leg active range of motion None major
[26] 1110 Active mobilization: 5267 session: in-bed exercise, in-bed bicycling, sitting, transfer, standing, walking 0.6 % Arrhythmia, MAP > 140 mmHg, MAP < 55 mmHg, oxygen desaturation, fall, feeding tube extraction, radial artery catheter removal, chest tube removal
[27] 637 16-level early progressive mobility protocol Not validated
[28] 99 Active mobilization: 520 sessions 5 % Respiratory distress, desaturation, tachypnea or bradycardia, patient’s intolerance, tracheostomy removal
[5] 120 Proper breathing techniques during exercise, progressive range of motion, muscle strengthening exercises, exercises designed to improve core mobility and strength, functional mobility retraining 0.16 % Syncopal episode during a PT session, readmitted to the hospital with polyarthralgia
[6] 50 Early goal-directed mobilization 0.96 % Fall, systolic blood pressure <90 mmHg, oxygen desaturation, feeding tube extraction, systolic blood pressure >200 mmHg
[7] 300 Passive range of motion, physical therapy, and progressive resistance exercises 6.0 % Deaths, device removals, reintubations, and patient falls during physical therapy