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Table 2 Adverse events during early mobilization

From: Early mobilization of mechanically ventilated patients in the intensive care unit

Reference #

n

Early mobilization intervention

Incidence of adverse events

Adverse events

[24]

103

Active mobilization: 1449 sessions: sitting on bed and in chair, ambulation

0.96 %

Fall, systolic blood pressure <90 mmHg, oxygen desaturation, feeding tube extraction, systolic blood pressure >200 mmHg

[3]

90

Passive and active therapy, bicycle ergometer exercise

3.76 %

SpO2 < 90 %, systolic blood pressure >180 mmHg, >20 % decrease in diastolic blood pressure

[2]

104

Passive and active range of motion, sitting, balance exercises, activities of daily living, transfer training, walking

4.0 %

Patient instability (most often because of perceived patient-ventilator asynchrony), 0.2 % serious (desaturation <80 %)

[29]

99

Active mobilization: 498 sessions

16 %

Desaturation ≧5 %, heart rate increase >20 %, ventilator asynchrony/tachypnea, agitation/discomfort, device removal

[25]

20

Active mobilization: 424 sessions: chair sitting, head up tilt, walking

3 %

Decreased muscle tone, hypoxemia, extubation, orthostatic, hypotension

[4]

150

Walking in place, sit to stand transfers, arm and leg active range of motion

None major

–

[26]

1110

Active mobilization: 5267 session: in-bed exercise, in-bed bicycling, sitting, transfer, standing, walking

0.6 %

Arrhythmia, MAP > 140 mmHg, MAP < 55 mmHg, oxygen desaturation, fall, feeding tube extraction, radial artery catheter removal, chest tube removal

[27]

637

16-level early progressive mobility protocol

Not validated

–

[28]

99

Active mobilization: 520 sessions

5 %

Respiratory distress, desaturation, tachypnea or bradycardia, patient’s intolerance, tracheostomy removal

[5]

120

Proper breathing techniques during exercise, progressive range of motion, muscle strengthening exercises, exercises designed to improve core mobility and strength, functional mobility retraining

0.16 %

Syncopal episode during a PT session, readmitted to the hospital with polyarthralgia

[6]

50

Early goal-directed mobilization

0.96 %

Fall, systolic blood pressure <90 mmHg, oxygen desaturation, feeding tube extraction, systolic blood pressure >200 mmHg

[7]

300

Passive range of motion, physical therapy, and progressive resistance exercises

6.0 %

Deaths, device removals, reintubations, and patient falls during physical therapy