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Table 2 Differences in different markers of acid-base disorders at ICU admission between survivors and non-survivors (n = 6878)

From: A comparison of prognostic significance of strong ion gap (SIG) with other acid-base markers in the critically ill: a cohort study

Acid-base markers Survivors (n = 5954) Non-survivors (n = 924) p valuea
1. Arterial pH 7.35 (7.29–7.39) 7.28 (7.17–7.37) 0.001
2. Arterial CO2 tension, mmHg 40 (35–45) 40 (34–48.8) 0.022
3. Actual bicarbonate conc., mmol/L 21 (19–23) 18 (14–21.8) 0.001
4. Chloride conc., mmol/L 110 (107–113) 109 (105–114) 0.891
5. Lactate conc., mmol/L 1.5 (1.0–2.4) 2.7 (1.4–5.6) 0.001
6. Actual base excess, mmol/L −3 (−6 to −1) −7 (−12 to −3) 0.001
7. Anion gap, mmol/L 12.5 (10.1–15.0) 15.0 (11.9–19.5) 0.001
8. Anion gap albumin-corrected, mmol/L 15.5 (12.8–18.5) 18.7 (14.8–23.6) 0.001
9. SIG with lactate, mmol/L 4.2 (1.5–7.1) 6.5 (3.0–10.8) 0.001
10. SIG without lactate, mmol/L 2.2 (−0.3 to 5.0) 2.5 (−0.4 to 5.8) 0.028
11. SID-effective, mmol/L 33.5 (30.5–36.2) 30.7 (26.7–34.7) 0.001
12. Other unmeasured ions, mmol/L 2.1 (−1.0 to 4.9) −1.5 (−7.3 to 2.5) 0.001
  1. All data are median values with the interquartile range reported in parenthesis
  2. CO 2 carbon dioxide, SID strong ion difference, SIG strong ion gap
  3. a p values generated by Mann-Whitney test