Table 1 Characteristics and physiology of patients after out-of-hospital cardiac arrest
Characteristic | All patients (n = 21) | Favourable group (n = 11) | Unfavourable group (n = 10) | P value |
|---|---|---|---|---|
Age—years, median (IQR) | 62.0 (47.0–79.0) | 67.0 (36.0–76.0) | 58.5 (47.0–83.0) | 0.647 |
Male sex—no. (%) | 13 (61.9 %) | 8 (72.7 %) | 5 (50 %) | 0.387 |
Type of bystander-witness status—no. (%) | 16 (76.2 %) | 8 (72.7 %) | 8 (80 %) | 1.000 |
Bystander-initiated CPR—no. (%) | 14 (66.7 %) | 7 (72.7 %) | 7 (70 %) | 1.000 |
Cardiac origin—no. (%) | 17 (81.0 %) | 10 | 7 | 0.311 |
Initially documented rhythms on the scene of cardiac arrest—no. | 0.123 | |||
VF/pulseless VT | 11 | 8 | 3 | |
Non-VF/pulseless VT | 10 | 3 | 7 | |
Estimated interval from collapse to ROSC—min | 16.5 (13.0–29.5) | 13.5 (10.0–16.25) | 23.5 (16.75–44.25) | 0.014 |
Therapeutic hypothermia—no. (%) | 14 (66.7 %) | 9 (81.8 %) | 5 (50 %) | 0.183 |
Initial lactate—mmol L−1 | 3.9 (2.4–7.5) | 12.1 (7.08–15.70) | 0.003 | |
Initial NH3—μg dl−1 | 90.0 (41.0–140.0) | 221.0 (90.5–345.5) | 0.025 | |
Myoglobin (day 1)—ng ml−1 | 402 (95–1343) | 2008 (323–8358) | 0.070 | |
APACHE-II | 24 (15–29) | 30 (26–37) | 0.072 | |
IL-6 (day 1)—pg ml−1 | 23.5 (13.9–53.9) | 88.0 (56.2–687.5) | 0.024 | |
Max IL-6—pg ml−1 | 84.9 (45.8–119.0) | 196.5 (82.4–30637.5) | 0.087 | |
Max JAAM DIC | 3.0 (2.0–4.0) | 4.0 (2.0–6.25) | 0.285 | |
Max ISTH DIC | 3.0 (2.0–3.0) | 3.0 (2.75–5.5) | 0.338 | |
Max SOFA | 10 (7.0–11.0) | 10.0 (8.75–13.5) | 0.499 | |
Max d-dimer | 7.0 (4.9–25.1) | 24.7 (4.9–25.1) | 0.074 | |
Neurological outcomes 30 days after OHCA | ||||
Survival (CPCs 1–4)—no. (%) | 14 (66.7 %) | |||
CPC 1, good performance | 9 | |||
CPC 2, moderate disability | 2 | |||
CPC 3, severe disability | 1 | |||
CPC 4, vegetative state | 2 | |||
CPC 5, death | 7 |