Fig. 5

Prognostic value of high-mobility group box 1, mitochondrial DNA, interleukin-6, and physiologic variables in patients with favourable and unfavourable neurological outcomes after out-of-hospital cardiac arrest. The areas under the receiver operating characteristic curves for high-mobility group box 1, mitochondrial DNA, interleukin-6, initial lactate, and Acute Physiology and Chronic Health Evaluation II score were 0.864, 0.573, 0.791, 0.877, and 0.732, respectively. The optimal cutoff value for high-mobility group box 1 was 22 ng ml⁻¹ with a specificity of 0.90 and a sensitivity of 0.80. HMGB-1 high-mobility group box 1, mtDNA mitochondrial DNA, APACHE-II Acute Physiology and Chronic Health Evaluation II