Sodium bicarbonate prophylactic therapy in the prevention of contrast-induced nephropathy in patients admitted to the intensive care unit of a teaching hospital: a retrospective cohort study

Table 5 Risk factors for contrast-induced nephropathy in intensive care unit patients (multivariate logistic regression analysis)

Variable	OR	p value
Prophylactic pre- and post-hydration (Y/N)	1.32	0.49
GFR < 60 mL/min or >60 mL/min	4.41	<0.01
APACHE IV score (per increasing point)	1.02	0.02
Norepinephrine use (Y/N)	1.49	0.32
Aminoglycoside use (Y/N)	3.87	0.05
Fluid balance (per ml)	1.00	0.95
Haemoglobin (>mmol/L)	0.64	0.03
Age (/year)	1.02	0.37

All variables that differed significantly between the no CIN and the CIN groups in a univariate test (Table 4) were included in the multivariate regression analysis, except for the APACHE II score. This score is highly correlated with APACHE IV and therefore was discarded from the multivariate analysis
GFR glomerular filtration rate, OR odds ratio, APACHE Acute Physiology and Chronic Health Evaluation

ISSN: 2052-0492