Comparison of total, salivary and calculated free cortisol levels in patients with severe sepsis

Elbuken, Gulsah; Karaca, Zuleyha; Tanriverdi, Fatih; Unluhizarci, Kursad; Sungur, Murat; Doganay, Mehmet; Kelestimur, Fahrettin

doi:10.1186/s40560-015-0125-0

Journal of Intensive Care

Table 2 Differences between STC, SaC, cFC and CBG levels of the patients who have survived or not

From: Comparison of total, salivary and calculated free cortisol levels in patients with severe sepsis

Days	Number	Survival	STC (μg/dL)		SaC (μg/dL)		cFC (μg/dL)		CBG (μg/dL)
Days	Number	Survival	Baseline	Peak	Baseline	Peak	Baseline	Peak	Baseline	Peak
D1	30	Alive	9.4 (3.1–25.8)	14.3 (7.4–46.9)	1.0 (0.2–7.5)	2.0 (0.6–15.0)	0.3 (0.1–0.9)	0.5 (0.3–1.7)	0.3 (0.1–0.6)	0.4 (0.2–0.5)
D1	30	Dead	21.0 (4.6–53.2)	31.0 (7.5–52.0)	2.3 (0.2–9.0)	3.4 (0.5–17.8)	0.8 (0.2–1.87)	1.1 (0.3–1.9)	0.2 (0.1–0.5)	0.3 (0.1–0.5)
D2	22	Alive	12.4 (4.9–40.9)		0.7 (0.1–3.3)		0.4 (0.2–1.4)		0.2 (0.1–0.5)
D2	22	Dead	17.7 (5.6–24.8)		0.6 (0.1–5.2)		0.8 (0.3–1.5)		0.2 (0.2–0.5)
D3	20	Alive	10.2 (3.2–31.3)		0.7 (0.1–3.8)		0.3 (0.1–1.1)		0.2 (0.1–0.5)
D3	20	Dead	22.8 (7.9–43.3)		0.9 (0.1–5.2)		0.8 (0.3–1.5)		0.2 (0.2–0.4)
D4	20	Alive	12.6 (3.5–22.1)		0.8 (0.1–3.0)		0.5 (0.1–0.8)		0.3 (0.1–0.4)
D4	20	Dead	18.6 (3.3–50.5)		2.2 (0.2–9.4)		0.7 (0.1–1.8)		0.3 (0.1–0.4)
D5	19	Alive	11.4 (5.2–30.4)		0.8 (0.1–4.6)		0.4 (0.2–1.1)		0.3 (0.1–0.4)
D5	19	Dead	20.2 (15.6–30.0)		0.7 (0.1–3.1)		0.7 (0.6–1.1)		0.2 (0.2–0.4)
D6	17	Alive	10.4 (2.1–43.0)		1.0 (0.1–4.6)		0.4 (0.1–1.5)		0.2 (0.1–0.5)
D6	17	Dead	27.3 (5.6–32.6)		2.0 (0.9–4)		1.0 (0.2–1.2)		0.3 (0.1–0.4)
D7	14	Alive	6.9 (0.4–13.9)	9.9 (3.9–25.0)	0.5 (0.3–3.0)	1.7 (0.2–4.0)	0.2 (0.1–0.5)	0.4 (0.1–0.9)	0.3 (0.2–0.5)	0.4 (0.2–0.5)
D7	14	Dead	8.7 (5.6–12.4)	13.3 (8.3–18.8)	0.9 (0.6–4.6)	2.4 (0.6–2.9)	0.3 (0.2–0.4)	0.5 (0.3–0.7)	0.3 (0.2–0.5)	0.3 (0.1–0.4)
p1			0.02	0.53	0.28	0.12	0.02	0.01	0.39	0.27
p2			0.08		0.64		0.57		0.56
p3			0.55		0.69		0.06		0.36
p4			0.02		0.32		0.55		0.91
p5			0.02		0.9		0.02		0.44
p6			0.3		0.2		0.3		0.5
p7			0.01	0.24	0.07	0.39	0.01	0.24	0.94	0.35

Abbreviations: STC serum total cortisol, SaC salivary cortisol, cFC calculated free cortisol, CBG cortisol binding globulin, D day of severe sepsis, p1, p2, p3, p4, p5, p6 and p7 belongs to comparisons between patients with severe sepsis on D1, D2, D3, D4, D5, D6 and D7 who have survived or not

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