Red cell transfusions as an independent risk for mortality in critically ill children

Table 7 Logistic regression analyses with only transfused subjects, with mortality as the dependent variable (n = 514)

Variable	Odds ratio	95 % confidence interval	p value
PIM2 score	1.59	1.10–2.28	0.013
PRISM III score	1.17	1.07–1.28	0.001
Age^a	0.90	0.82–0.98	0.016
Transfusion^b
<0 h	0.06	0.002–2.00	0.118
0 h to <24 h	0.08	0.02–0.32	<0.001
>48 h	0.36	0.10–1.33	0.124
Gender	2.80	0.95–8.25	0.062
Vasoactive agents	4.94	1.37–17.86	0.015
Day 1 PELOD score	1.06	0.99–1.13	0.117
Reason for PICU admission^c
Cardiovascular	0.14	0.03–0.66	0.013
Neurologic	2.37	0.41–13.78	0.338
Trauma	0.81	0.12–5.42	0.830
Other^d	1.27	0.27–5.90	0.759

^aAll ages divided by 10 prior to analysis
^bRefers to timing of transfusion relative to ICU admission; <0 h group was transfused prior to ICU admission; the reference group was transfused within the 24–48 h time frame
^cReason for PICU admission, odds ratio relative to respiratory (reference group)
^dOther includes all other categories (e.g., endocrinologic, gastrointestinal, infectious, oncologic)

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