Variables
| | | |
Age (year) mean ± SD
|
65.3 ± 15.6
|
61.8 ± 17.3
|
0.013
|
<40 (n, %)
|
11 (6.8)
|
537 (12.5)
| |
40–70 (n, %)
|
76 (47.0)
|
2175 (50.7)
| |
>70 (n, %)
|
75 (46.2)
|
1576 (36.8)
| |
Male (n, %)
|
102 (63.0)
|
2505 (58.4)
|
0.249
|
Body mass index (kg/m2) (mean ± SD)
|
22.0 ± 4.6
|
23.0 ± 5.7
|
0.031
|
ASA PS (n, %)
| | |
<0.001
|
I–II
|
26 (23.6)
|
1291(39.0)
| |
III
|
58 (52.7)
|
1620 (49.0)
| |
IV–VI
|
26 (23.6)
|
392 (12.0)
| |
Comorbidity (n, %)
| | | |
Hypertension
|
75 (46.3)
|
2130 (49.7)
|
0.399
|
Diabetes mellitus
|
33 (20.4)
|
946 (22.1)
|
0.610
|
Coronary artery disease
|
15 (9.4)
|
433 (10.1)
|
0.728
|
Congestive heart failure
|
11 (6.8)
|
93 (2.2)
|
<0.001
|
COPD
|
21 (12.9)
|
184 (4.3)
|
<0.001
|
Chronic renal failure
|
25 (15.4)
|
406 (9.5)
|
0.012
|
Smoking history (n, %)
| | |
<0.001
|
Current smokers
|
32 (19.7)
|
498 (11.6)
| |
Ex-smokers
|
50 (30.8)
|
1054 (24.6)
| |
Non smokers
|
80 (49.4)
|
2736 (63.8)
| |
Numbers of pack years median (P25–75)
|
15.5( 10–25)
|
15 (6–30)
|
0.631
|
Numbers of operative patients (n, %)
|
119 (73.5)
|
3377 (79.8)
|
0.118
|
Sites of SICU (n, %)
| | |
<0.001
|
Site A (incidence 1.9 %)
|
18 (11.1)
|
922 (21.5)
| |
Site B (incidence 1.2 %)
|
5 (3.1)
|
404 (9.4)
| |
Site C (incidence 2.7 %)
|
15 (9.3)
|
545 (12.7)
| |
Site D (incidence 1.9 %)
|
8 (5.0)
|
402 (9.3)
| |
Site E (incidence 0.8 %)
|
3 (1.8)
|
390 (9.1)
| |
Site F (incidence 0 %)
|
0
|
139 (3.2)
| |
Site G (incidence 13.9 %)
|
109 (67.3)
|
675 (15.7)
| |
Site H (incidence 0.8 %)
|
3 (1.8)
|
368 (8.6)
| |
Site I (incidence 0.2 %)
|
1 (0.6)
|
443 (10.5)
| |
Emergency surgery (n, %)
|
79 (66.4)
|
987 (29.2)
|
<0.001
|
Site of surgery (n, %)
| | | |
Upper abdomen
|
56 (34.6)
|
1182 (27.6)
|
0.051
|
Lower abdomen
|
43 (26.5)
|
1178 (27.5)
|
0.795
|
Thoracic
|
15 (9.8)
|
162 (3.8)
|
<0.001
|
Vascular
|
5 (3.1)
|
134 (3.1)
|
0.978
|
Extremities
|
14 (8.6)
|
371 (8.3)
|
0.883
|
Anus
|
1 (0.62)
|
52 (1.2)
|
0.493
|
Other surgeries
|
28 (17.2)
|
1209 (28.2)
|
0.001
|
Duration of surgery (min) median (P25–75)
|
180 (105–275)
|
240 (150–360)
|
<0.001
|
Amount of PRC transfusion (ml) median (P25–75)
|
100 (0–635)
|
0 (0–511)
|
0.274
|
Amount of FFP transfusion (ml) median (P25–75)
|
0 (0–780)
|
0 (0–0)
|
<0.001
|
APACHE II median (P25–75)
|
16 (12–23)
|
10 (7–15)
|
<0.001
|
SOFA median (P25–75)
|
5 (2–8)
|
2 (1–5)
|
<0.001
|
Sepsis (n, %)
|
109 (67.3)
|
779 (18.2)
|
<0.001
|
Mechanical ventilation (n, %)
|
141 (87.0)
|
2635 (61.8)
|
<0.001
|
Albumin (g/dl) (mean ± SD)
|
2.4 ± 0.85
|
2.8 ± 0.80
|
<0.001
|
Hemoglobin (g/dl) (mean ± SD)
|
9.7 ± 2.6
|
10.6 ± 2.1
|
<0.001
|
Blood sugar (mg%) (mean ± SD)
|
144.0 ± 72.0
|
164.1 ± 68.8
|
0.013
|
PaO2 (mmHg) (mean ± SD)
|
144.0 ± 72.1
|
164.1 ± 0.81
|
0.013
|
Exposure to sedative drugs (n, %)
|
110 (67.9)
|
932 (21.7)
|
<0.001
|
Exposure to analgesic drugs (n, %)
|
134(82.7)
|
3683 (85.9)
|
0.256
|
ICU admission diagnosis (n, %)
| | |
0.005
|
Abdominal
|
71 (43.8)
|
1728 (40.3)
| |
Cardiovascular
|
31 (19.1)
|
662 (15.4)
| |
Respiratory
|
17 (10.5)
|
335 (7.8)
| |
Renal
|
10 (6.2)
|
356 (8.3)
| |
Other
|
33 (20.4)
|
1207 (28.2)
| |
Prognostic outcomes
| | | |
Ventilator days (days) median (P25–75)
|
7 (4–17)
|
2 (1–4)
|
<0.001
|
Length of ICU stay (days) median (P25–75)
|
8 (5–19)
|
2 (1–4)
|
<0.001
|
Duration of hospital stay (days) median(P25–75)
|
22 (14–34)
|
15 (9–26)
|
<0.001
|
ICU mortality (n, %)
|
38 (23.5)
|
349 (8.1)
|
<0.001
|
28-day mortality (n, %)
|
45 (27.8)
|
534 (12.4)
|
<0.001
|