Table 2 Demographic and baseline parameters of the study population

Number of patients (n)

60

50

Gender (n, male)

44 (73 %)

36 (72 %)

n.s.

Age (years)

68 ± 12

69 ± 11

n.s.

Bodyweight (kg)

87 ± 21

86 ± 23

n.s.

Sepsis (n)

16 (27 %)

16 (32 %)

n.s.

Postoperative (n)

40 (66 %)

25 (50 %)

n.s.

Other reason for ICU admission (n)

4 (7 %)

9 (18 %)

n.s.

SOFA score at initiation of CRRT

10 ± 3

9 ± 3

n.s.

Creatinine before present illness (μmol/l)

195 ± 139

226 ± 252

n.s.

Creatinine at initiation of CRRT (μmol/l)

337 ± 133

343 ± 179

n.s.

Urea before present illness (mmol/l)

11 ± 9

10 ± 9

n.s.

Urea at initiation of CRRT (mmol/l)

23 ± 9

22 ± 9

n.s.

Mean platelet count during CRRT (G/l)

168 ± 108

175 ± 115

n.s.

Mean dose of CRRT (ml∙h⁻¹∙kg body weight⁻¹)

24.0 ± 6.2

20.7 ± 5.6

0.0001

Mean blood flow (ml/min)

102 ± 12.5

100 ± 2.8

n.s.

Mean dialysate flow (ml/h)

2035 ± 307

1133 ± 283

0.0001

Mean flow replacement fluid (ml/h)

–

563 ± 203

n.a.

Mean ultrafiltration flow (ml/h)

159 ± 55

170 ± 59

0.0001

Mechanical ventilation (n)

43 (72 %)

40 (80 %)

n.s.

Cirrhosis of the liver (n)

6 (10 %)

4 (8 %)

n.s.

Patients weaned from CRRT (n)

22 (37 %)

19 (38 %)

n.s.

Patients receiving intermittent dialysis at ICU discharge (n)

8 (13 %)

4 (8 %)

n.s.

Fatal outcome on ICU (n)

30 (50 %)

27 (54 %)

n.s.