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Table 1 Alteration of lower than class level bacteria in colon microbiota

From: Persistent hyperglycemia modulates gut immune function and microbiota in rats

  CN group (detection rate) CH group (detection rate) EN group (detection rate) EH group (detection rate) Factor A (C vs E) Factor B (N vs H) Factor A*B
Total bacterial counts 9.4 ± 0.2 (6/6) 9.8 ± 0.8 (7/7) 10.1 ± 0.4 (6/6) 9.7 ± 1.1 (7/8) P = 0.43 P = 0.98 P = 0.31
Obligate anaerobe        
Clostridium coccoides group 7.8 ± 0.3 (6/6) 8.6 ± 0.5 (7/7) 9.1 ± 0.4 (6/6) 8.7 ± 1.1 (7/7) P = 0.10 P = 0.67 P = 0.11
C. leptum subgroup 8.2 ± 0.5 (6/6) 8.9 ± 0.7 (7/7) 9.5 ± 0.3 (6/6) 8.8 ± 1.1 (7/7) P = 0.17 P = 0.99 P = 0.12
C. perfringens <2.3 (6/6) 3.5 ± 1.6 (4/7) 5.1 ± 1.2 (6/6) 4.7 ± 1.1 (6/7) P < 0.01 P = 0.39 P = 0.12
Bifidobacterium 7.7 ± 0.6 (6/6) 6.4 ± 1.2 (7/7) 6.4 ± 1 (5/6) 6.5 ± 0.9 (6/7) P = 0.09 P = 0.13 P = 0.06
Atopobium cluster 8.1 ± 0.4 (6/6) 7.4 ± 1 (6/7) 7.7 ± 0.5 (6/6) 7.6 ± 0.8 (7/7) P = 0.1 P = 0.16 P = 0.57
Prevotella 5.9 ± 1.1 (3/6) 6.4 ± 1.4 (4/7) 7.2 ± 0.4 (6/6) 6.6 ± 1.1 (7/7) P = 0.12 P = 0.90 P = 0.24
Bacteroides fragilis group 7.9 ± 0.5 (6/6) 7.6 ± 1.2 (7/7) <5.0 (0/6) 7.2 (1/7) P < 0.01 P = 0.97 P = 0.44
Facultative anaerobe        
L. gasseri subgroup 9.1 ± 0.5 (6/6) 9.5 ± 1.2 (7/7) 9.9 ± 0.6 (6/6) 9.4 ± 1.3 (7/7) P = 0.46 P = 0.97 P = 0.41
L. brevis <2.3 (6/6) 2.9 ± 1 (2/7) 3.4 ± 0.8 (6/6) 3.0 ± 0.9 (3/7) P = 0.08 P = 0.75 P = 0.19
L. casei subgroup <3.2 (0/6) <3.2 (0/7) <3.2 (0/6) <3.2 (0/7) - - -
L. fermentum <4.0 (0/6) <4.0 (0/7) <4.0 (0/6) <4.0 (0/7) - - -
L. plantarum subgroup <2.9 (0/6) <2.9 (0/7) <2.9 (0/6) <2.9 (0/7) - - -
L. reuteri subgroup 7.7 ± 0.7 (6/6) 4.9 ± 2.8 (4/7) * 2.8 ± 0.9 (4/6) 2.8 ± 0.8 (5/7) - - P < 0.05
L. ruminis subgroup 4.5 ± 0.8 (6/6) 4.4 ± 1.1 (6/7) 7.2 ± 1.3 (6/6) 5.3 ± 1.7 (7/7) P = 0.07 P < 0.01 P = 0.05
L. sakei subgroup 2.5 ± 0.4 (3/6) 2.8 ± 0.6 (6/7) 2.9 ± 0.7 (5/6) 2.9 ± 0.8 (5/7) P = 0.38 P = 0.69 P = 0.57
Staphylococcus 5.1 ± 0.7 (6/6) 6.7 ± 1 (7/7) ** 6.3 ± 0.7 (6/6) 5.4 ± 1.4 (6/7) - - P < 0.01
Enterococcus 6.7 ± 1 (6/6) 7 ± 0.7 (7/7) 7.8 ± 0.7 (6/6) 6.8 ± 0.8 (7/7) *** - - P < 0.05
Enterobacteriaceae 6.6 ± 1 (6/6) 7 ± 1.5 (6/7) 8.8 ± 0.3 (6/6) 7.6 ± 0.6 (7/7) **** - - P < 0.05
Aerobes        
Pseudomonas species <3.0 (0/6) <3.0 (0/7) <3.0 (0/6) <3.0 (0/7) - - -
  1. The numbers are presented as logalithm10 cells/g of colon contents
  2. Data indicates mean ± SD (log10 cells/g of colon contents)
  3. *: P < 0.05 versus CN group, **: P < 0.01 versus CN group, ***: P < 0.05 versus EN group, ****: P < 0.01 versus EN group