From: Persistent hyperglycemia modulates gut immune function and microbiota in rats
CN group (detection rate) | CH group (detection rate) | EN group (detection rate) | EH group (detection rate) | Factor A (C vs E) | Factor B (N vs H) | Factor A*B | |
---|---|---|---|---|---|---|---|
Total bacterial counts | 9.4 ± 0.2 (6/6) | 9.8 ± 0.8 (7/7) | 10.1 ± 0.4 (6/6) | 9.7 ± 1.1 (7/8) | P = 0.43 | P = 0.98 | P = 0.31 |
Obligate anaerobe | |||||||
Clostridium coccoides group | 7.8 ± 0.3 (6/6) | 8.6 ± 0.5 (7/7) | 9.1 ± 0.4 (6/6) | 8.7 ± 1.1 (7/7) | P = 0.10 | P = 0.67 | P = 0.11 |
C. leptum subgroup | 8.2 ± 0.5 (6/6) | 8.9 ± 0.7 (7/7) | 9.5 ± 0.3 (6/6) | 8.8 ± 1.1 (7/7) | P = 0.17 | P = 0.99 | P = 0.12 |
C. perfringens | <2.3 (6/6) | 3.5 ± 1.6 (4/7) | 5.1 ± 1.2 (6/6) | 4.7 ± 1.1 (6/7) | P < 0.01 | P = 0.39 | P = 0.12 |
Bifidobacterium | 7.7 ± 0.6 (6/6) | 6.4 ± 1.2 (7/7) | 6.4 ± 1 (5/6) | 6.5 ± 0.9 (6/7) | P = 0.09 | P = 0.13 | P = 0.06 |
Atopobium cluster | 8.1 ± 0.4 (6/6) | 7.4 ± 1 (6/7) | 7.7 ± 0.5 (6/6) | 7.6 ± 0.8 (7/7) | P = 0.1 | P = 0.16 | P = 0.57 |
Prevotella | 5.9 ± 1.1 (3/6) | 6.4 ± 1.4 (4/7) | 7.2 ± 0.4 (6/6) | 6.6 ± 1.1 (7/7) | P = 0.12 | P = 0.90 | P = 0.24 |
Bacteroides fragilis group | 7.9 ± 0.5 (6/6) | 7.6 ± 1.2 (7/7) | <5.0 (0/6) | 7.2 (1/7) | P < 0.01 | P = 0.97 | P = 0.44 |
Facultative anaerobe | |||||||
L. gasseri subgroup | 9.1 ± 0.5 (6/6) | 9.5 ± 1.2 (7/7) | 9.9 ± 0.6 (6/6) | 9.4 ± 1.3 (7/7) | P = 0.46 | P = 0.97 | P = 0.41 |
L. brevis | <2.3 (6/6) | 2.9 ± 1 (2/7) | 3.4 ± 0.8 (6/6) | 3.0 ± 0.9 (3/7) | P = 0.08 | P = 0.75 | P = 0.19 |
L. casei subgroup | <3.2 (0/6) | <3.2 (0/7) | <3.2 (0/6) | <3.2 (0/7) | - | - | - |
L. fermentum | <4.0 (0/6) | <4.0 (0/7) | <4.0 (0/6) | <4.0 (0/7) | - | - | - |
L. plantarum subgroup | <2.9 (0/6) | <2.9 (0/7) | <2.9 (0/6) | <2.9 (0/7) | - | - | - |
L. reuteri subgroup | 7.7 ± 0.7 (6/6) | 4.9 ± 2.8 (4/7) * | 2.8 ± 0.9 (4/6) | 2.8 ± 0.8 (5/7) | - | - | P < 0.05 |
L. ruminis subgroup | 4.5 ± 0.8 (6/6) | 4.4 ± 1.1 (6/7) | 7.2 ± 1.3 (6/6) | 5.3 ± 1.7 (7/7) | P = 0.07 | P < 0.01 | P = 0.05 |
L. sakei subgroup | 2.5 ± 0.4 (3/6) | 2.8 ± 0.6 (6/7) | 2.9 ± 0.7 (5/6) | 2.9 ± 0.8 (5/7) | P = 0.38 | P = 0.69 | P = 0.57 |
Staphylococcus | 5.1 ± 0.7 (6/6) | 6.7 ± 1 (7/7) ** | 6.3 ± 0.7 (6/6) | 5.4 ± 1.4 (6/7) | - | - | P < 0.01 |
Enterococcus | 6.7 ± 1 (6/6) | 7 ± 0.7 (7/7) | 7.8 ± 0.7 (6/6) | 6.8 ± 0.8 (7/7) *** | - | - | P < 0.05 |
Enterobacteriaceae | 6.6 ± 1 (6/6) | 7 ± 1.5 (6/7) | 8.8 ± 0.3 (6/6) | 7.6 ± 0.6 (7/7) **** | - | - | P < 0.05 |
Aerobes | |||||||
Pseudomonas species | <3.0 (0/6) | <3.0 (0/7) | <3.0 (0/6) | <3.0 (0/7) | - | - | - |