Procalcitonin-guided antibiotic therapy for septic patients in the surgical intensive care unit

Table 3 Procalcitonin diagnostic levels for sepsis in prospective studies in ICU populations

Name	Year	Number	Ref	PCT <0.5	0.6 to <1.0	1.1 to <1.5	1.6 to 2.0	Sensitivity (%)	Specificity (%)
Al-Nawas	1996	337	[32]	0.5				60	79
Bossink	1999	200	[33]	0.5				65	58
Sudhir	2011	100	[34]	0.5				94	–
Ugarte	1999	205	[35]		0.6			68	61
Muller	2000	101	[36]		1.0			89	94
Aouifi	2000	97	[37]		1.0			85	95
Ruokonen	2002	208	[38]		0.8			68	48
G-B	2002	119	[39]		1.0			95	65
Whang	1998	29	[40]			1.1		67	80
Oberhoffer	2000	242	[41]			1.4		84	83
Wanner	2000	405	[42]			1.5		76^a	77
Harbarth	2001	78	[9]			1.1		97	78
Tugrul	2002	85	[43]			1.3		73	83
Hensler	2003	137	[44]			1.5		42^a	73
Castelli	2004	150	[18]			1.1		79	85
Mokart	2005	50	[45]			1.1		81	72
Brunkhorst	2000	185	[46]				2.0	96	86
Suprin	2000	101	[47]				2.0	65	70
Meisner	2002	208	[48]				2.0	87	78
DeTalance	2003	108	[49]				2.0	91	89
Luzzani	2003	70	[50]				2.0	76	84
Du	2003	51	[51]				1.6	80	74
Geppert	2003	55	[52]				2.0	87	75
Endo	2008	82	[53]				2.0	95	78
Meynaar	2011	76	[54]				2.0	97	80

^aThese studies included trauma patients, PCT is known to rise after trauma unrelated to sepsis
ref reference

ISSN: 2052-0492