|
Antifungal therapy (n = 102)
|
No antifungal therapy (n = 220)
|
p value
|
---|
SOFA score (day 7)
|
6 (3; 9)
|
3 (2; 7)
|
0.003
|
Lung
|
1 (1; 2)
|
1 (1; 2)
|
0.034
|
Thrombocytes
|
1 (0; 2)
|
0 (0; 2)
|
0.236
|
Liver
|
0 (0; 1)
|
0 (0; 0)
|
0.001
|
Cardiovascular
|
0 (0; 3)
|
0 (0; 3)
|
0.033
|
Renal
|
1 (0; 2)
|
1 (0; 2)
|
0.159
|
New pneumonia, n (%)
|
21 (20.6)
|
22 (10)
|
0.013
|
Sepsis, n (%)
| | | |
Sepsis/severe sepsis
|
27 (26.5)
|
26 (11.8)
|
0.002
|
Septic shock
|
29 (28.4)
|
32 (14.5)
|
0.006
|
Duration of mechanical ventilation (h)
|
362 (199; 599)
|
160 (67; 284)
|
<0.001
|
Hospital stay (days)
|
31 (17; 53)
|
21 (12; 35)
|
<0.001
|
ICU stay (days)
|
20 (11; 29)
|
8 (4; 14)
|
<0.001
|
In-hospital mortality, n (%)
|
53 (52.0)
|
76 (34.5)
|
0.003
|
Discharge from hospital, n (%)
| | | |
Other hospital
|
24 (23.5)
|
47 (21.4)
|
0.667
|
Rehabilitation clinic
|
19 (18.6)
|
42 (19.1)
|
1
|
Home
|
6 (5.9)
|
49 (22.3)
|
<0.001
|
Others
|
0 (0)
|
6 (2.7)
|
0.032
|
- Data are presented as median (25 %; 75 % quartile)
- SOFA Sequential Organ Failure Assessment, ICU intensive care unit