Table 2 Outcome characteristics of patients with isolated pulmonary Candida spp. colonization (cohort 1)
Antifungal therapy (n = 102) | No antifungal therapy (n = 220) | p value | |
|---|---|---|---|
SOFA score (day 7) | 6 (3; 9) | 3 (2; 7) | 0.003 |
Lung | 1 (1; 2) | 1 (1; 2) | 0.034 |
Thrombocytes | 1 (0; 2) | 0 (0; 2) | 0.236 |
Liver | 0 (0; 1) | 0 (0; 0) | 0.001 |
Cardiovascular | 0 (0; 3) | 0 (0; 3) | 0.033 |
Renal | 1 (0; 2) | 1 (0; 2) | 0.159 |
New pneumonia, n (%) | 21 (20.6) | 22 (10) | 0.013 |
Sepsis, n (%) | |||
Sepsis/severe sepsis | 27 (26.5) | 26 (11.8) | 0.002 |
Septic shock | 29 (28.4) | 32 (14.5) | 0.006 |
Duration of mechanical ventilation (h) | 362 (199; 599) | 160 (67; 284) | <0.001 |
Hospital stay (days) | 31 (17; 53) | 21 (12; 35) | <0.001 |
ICU stay (days) | 20 (11; 29) | 8 (4; 14) | <0.001 |
In-hospital mortality, n (%) | 53 (52.0) | 76 (34.5) | 0.003 |
Discharge from hospital, n (%) | |||
Other hospital | 24 (23.5) | 47 (21.4) | 0.667 |
Rehabilitation clinic | 19 (18.6) | 42 (19.1) | 1 |
Home | 6 (5.9) | 49 (22.3) | <0.001 |
Others | 0 (0) | 6 (2.7) | 0.032 |