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Table 2 Outcome characteristics of patients with isolated pulmonary Candida spp. colonization (cohort 1)

From: Antifungal therapy in patients with pulmonary Candida spp. colonization may have no beneficial effects

  Antifungal therapy (n = 102) No antifungal therapy (n = 220) p value
SOFA score (day 7) 6 (3; 9) 3 (2; 7) 0.003
 Lung 1 (1; 2) 1 (1; 2) 0.034
 Thrombocytes 1 (0; 2) 0 (0; 2) 0.236
 Liver 0 (0; 1) 0 (0; 0) 0.001
 Cardiovascular 0 (0; 3) 0 (0; 3) 0.033
 Renal 1 (0; 2) 1 (0; 2) 0.159
New pneumonia, n (%) 21 (20.6) 22 (10) 0.013
Sepsis, n (%)    
 Sepsis/severe sepsis 27 (26.5) 26 (11.8) 0.002
 Septic shock 29 (28.4) 32 (14.5) 0.006
Duration of mechanical ventilation (h) 362 (199; 599) 160 (67; 284) <0.001
Hospital stay (days) 31 (17; 53) 21 (12; 35) <0.001
ICU stay (days) 20 (11; 29) 8 (4; 14) <0.001
In-hospital mortality, n (%) 53 (52.0) 76 (34.5) 0.003
Discharge from hospital, n (%)    
 Other hospital 24 (23.5) 47 (21.4) 0.667
 Rehabilitation clinic 19 (18.6) 42 (19.1) 1
 Home 6 (5.9) 49 (22.3) <0.001
 Others 0 (0) 6 (2.7) 0.032
  1. Data are presented as median (25 %; 75 % quartile)
  2. SOFA Sequential Organ Failure Assessment, ICU intensive care unit