Fig. 1

Flow chart illustrating the recruitment process. 500 patients were eligible for this study. Cohort 1: 322 patients with isolated pulmonary Candida spp. colonization with or without pre-existing pneumonia after excluding 178 patients with multifocal colonization. Cohort 2: 175 patients with isolated pulmonary Candida spp. colonization without any pre-existing pneumonia (therapy group: n = 44; control group: n = 131) after excluding 147 patients who had a pre-existing pneumonia before enrollment