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Table 2 Patients’ data by ICU chart review in the Dex and the non-Dex groups

From: Dexmedetomidine sedation during the nighttime reduced the incidence of postoperative atrial fibrillation in cardiovascular surgery patients after tracheal extubation

 

Day 1

Day 2

 

Dex group (n = 16)

Non-Dex group (n = 29)

p value

Dex group (n = 16)

Non-Dex group (n = 27)

p value

Dex dose (μg/kg/h)

0.3 ± 0.1

0

 

0.3 ± 0.2

0

 

HR daytime (bpm)

79.5 ± 7.4

84.2 ± 12.8

0.18

79.0 ± 8.7

82.8 ± 14.9

0.37

HR nighttime (bpm)

73.5 ± 13.0

84.4 ± 9.3

0.002

69.9 ± 11.3

84.3 ± 9.6

<0.001

CVP (mmHg)

6.6 ± 2.7

7.5 ± 2.7

0.36

6.9 ± 2.4

7.5 ± 3.4

0.59

Body temperature (°C)

37.5 ± 0.4

37.7 ± 0.4

0.08

37.5 ± 0.5

37.6 ± 0.4

0.27

WBC (103/μl)

12.3 ± 4.8

11.8 ± 4.3

0.76

10.5 ± 4.7

10.2 ± 3.3

0.80

CRP (mg/dl)

8.8 ± 4.6

9.2 ± 5.1

0.82

7.8 ± 4.4

8.2 ± 4.0

0.76

Catecholamine use ≧3 μg/kg/m

2/16

9/29

0.17

5/16

5/27

0.27

Beta-blocker use

8/16

13/29

0.74

8/16

13/27

0.91

Amount of fentanyl (μg)

383.1 ± 339.2

429.3 ± 346.7

0.67

121.9 ± 140.6

179.3 ± 231.9

0.37

  1. The data are presented as mean ± standard deviation or the number of patients (%). Day 1: 24 h from 8 p.m. on the extubation day to 8 p.m. on the next day. Day 2: 24 h from 8 p.m. on the next day to 8 p.m. 2 days later following the extubation day. Catecholamine: dopamine and/or dobutamine
  2. ICU intensive care unit, Dex dexmedetomidine, HR heart rate, CVP central venous pressure, WBC white blood cell count, CRP serum level of C-reactive protein
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Journal of Intensive Care

ISSN: 2052-0492