From: Pharmacokinetics and the optimal regimen for levofloxacin in critically ill patients receiving continuous hemodiafiltration
Patient
CL total (l/h)
t 1/2 (h)
C max (mcg/ml)
AUC [(mg/l) h]
1
4.62
13.1
5.7
108.3
2
12.3
14.4
3.0
40.8
3
6.64
28.9
4.7
75.3
4
7.01
11.4
4.4
71.3
Mean ± SE
7.63 + 1.6
16.9 + 4.0
4.5 + 0.6
73.9 + 13.8