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Table 4 Risk factors for new-onset atrial fibrillation

From: Epidemiology, prevention, and treatment of new-onset atrial fibrillation in critically ill: a systematic review

Category

Risk factor

OR (95%CI)

Reference

Demographics

Age > 65 years

7.0 (2.0–24.6)

[58]

Age ≥ 40 years

6.3 (1.4–28.7)

[51]

Age ≥ 75 years

4.79 (1.16–19.8)

[52]

Age, per 10 years

1.52 (1.47–1.56)

[54]

Advanced age

1.04 (1.01–1.07)

[50]

Female sex

0.83 (0.76–0.90)

[54]

Hispanic (white as reference)

0.58 (0.50–0.63)

[54]

Black (white as reference)

0.67 (0.58–0.78)

[54]

Past history

Calcium channel blockers

3.87 (1.18–12.7)

[50]

Prior stroke

1.64 (1.35–2.01)

[54]

Metastatic/hematologic malignancy

1.23 (1.09–1.39)

[54]

Obesity

1.20 (1.03–1.40)

[54]

Hypertension

0.88 (0.81–0.95)

[54]

Diabetes mellitus

0.82 (0.75–0.90)

[54]

Severity

SAPS II ≥ 30

11.6 (1.3–103.0)

[51]

Shock

6.77 (2.17–21.1)

[50]

SIRS

4.4 (1.2–16.1)

[51]

APACHE II score ≥ 20

3.90 (1.00–16.7)

[52]

Organ failure

Respiratory failure

2.81 (2.48–3.19)

[54]

Congestive heart failure

1.61 (1.41–1.83)

[54]

Hematologic failure

1.50 (1.34–1.68)

[54]

Renal failure

1.40 (1.26–1.56)

[54]

Per organ failure

1.12 (1.05–1.19)

[54]

Acidosis

0.87 (0.77–0.97)

[54]

Trauma

Blunt thoracic trauma

16.8 (4.00–71.2)

[50]

Three or more regions traumatized

6.2 (1.8–21.4)

[51]

Infection

Sepsis

6.5 (2.0–21.1)

[57]

Sepsis at admission

4.87 (1.24–18.8)

[52]

Abdominal infection

1.77 (1.59–1.97)

[54]

Fungal infection

1.59 (1.27–2.00)

[54]

Respiratory tract infection

1.27 (1.14–1.40)

[54]

Skin or soft tissue infection

1.33 (1.14–1.55)

[54]

Gram-positive bacteria

1.29 (1.18–1.55)

[54]

Primary bacteremia

1.17 (1.02–1.36)

[54]

Urinary tract infection

0.89 (0.81–0.99)

[54]

Intervention

Catecholamine use

5.7 (1.7–19.1)

[51]

Pulmonary artery catheter

5.46 (1.84–16.2)

[50]

Right heart catheterization

2.25 (1.87–2.70)

[54]

  1. OR odds ratio, APACHE II Acute Physiology and Chronic Health Evaluation II, CI confidence interval, SAPS II Simplified Acute Physiology Score II, SIRS systemic inflammatory response syndrome.