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Table 4 Risk factors for new-onset atrial fibrillation

From: Epidemiology, prevention, and treatment of new-onset atrial fibrillation in critically ill: a systematic review

Category Risk factor OR (95%CI) Reference
Demographics Age > 65 years 7.0 (2.0–24.6) [58]
Age ≥ 40 years 6.3 (1.4–28.7) [51]
Age ≥ 75 years 4.79 (1.16–19.8) [52]
Age, per 10 years 1.52 (1.47–1.56) [54]
Advanced age 1.04 (1.01–1.07) [50]
Female sex 0.83 (0.76–0.90) [54]
Hispanic (white as reference) 0.58 (0.50–0.63) [54]
Black (white as reference) 0.67 (0.58–0.78) [54]
Past history Calcium channel blockers 3.87 (1.18–12.7) [50]
Prior stroke 1.64 (1.35–2.01) [54]
Metastatic/hematologic malignancy 1.23 (1.09–1.39) [54]
Obesity 1.20 (1.03–1.40) [54]
Hypertension 0.88 (0.81–0.95) [54]
Diabetes mellitus 0.82 (0.75–0.90) [54]
Severity SAPS II ≥ 30 11.6 (1.3–103.0) [51]
Shock 6.77 (2.17–21.1) [50]
SIRS 4.4 (1.2–16.1) [51]
APACHE II score ≥ 20 3.90 (1.00–16.7) [52]
Organ failure Respiratory failure 2.81 (2.48–3.19) [54]
Congestive heart failure 1.61 (1.41–1.83) [54]
Hematologic failure 1.50 (1.34–1.68) [54]
Renal failure 1.40 (1.26–1.56) [54]
Per organ failure 1.12 (1.05–1.19) [54]
Acidosis 0.87 (0.77–0.97) [54]
Trauma Blunt thoracic trauma 16.8 (4.00–71.2) [50]
Three or more regions traumatized 6.2 (1.8–21.4) [51]
Infection Sepsis 6.5 (2.0–21.1) [57]
Sepsis at admission 4.87 (1.24–18.8) [52]
Abdominal infection 1.77 (1.59–1.97) [54]
Fungal infection 1.59 (1.27–2.00) [54]
Respiratory tract infection 1.27 (1.14–1.40) [54]
Skin or soft tissue infection 1.33 (1.14–1.55) [54]
Gram-positive bacteria 1.29 (1.18–1.55) [54]
Primary bacteremia 1.17 (1.02–1.36) [54]
Urinary tract infection 0.89 (0.81–0.99) [54]
Intervention Catecholamine use 5.7 (1.7–19.1) [51]
Pulmonary artery catheter 5.46 (1.84–16.2) [50]
Right heart catheterization 2.25 (1.87–2.70) [54]
  1. OR odds ratio, APACHE II Acute Physiology and Chronic Health Evaluation II, CI confidence interval, SAPS II Simplified Acute Physiology Score II, SIRS systemic inflammatory response syndrome.