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Table 3 Patient characteristics of improvement group and non-improvement group

From: Polymyxin B-immobilized fiber column hemoperfusion mainly helps to constrict peripheral blood vessels in treatment for septic shock

  Improvement ( n = 42) Non-improvement ( n = 36) p value
Sex (male/female) 24/18 26/10 0.237
Age (years) 69 (13) 71 (34) 0.996
APACHE II score 24 (12) 24 (12) 0.980
SOFA score 11 (4) 11 (7) 0.996
MAP at baseline (mmHg) 62 (10) 72 (22) 0.343
Creatinine at baseline (mg/dl) 1.28 (1.72) 1.65 (1.85) 1.000
Lactate level at baseline (mmol/L) 3.2 (5.9) 4.2 (4.9) 0.599
Patients with diabetes mellitus 13 11 1.000
Patients received corticosteroid therapy 8 5 0.762
The times of PMX therapy 1 (1) 1 (1) 0.281
Total PMX treatment time (min) 1598 (2972) 1412 (2254) 0.237
Inotropic score at pre-PMX 24.7 (21.0) 10.3 (18.6) 0.001
Inotropic score at post-PMX 6.8 (15.6) 16.6 (32.8) 0.037
Vasopressor dependency index at pre-PMX (/mmHg) 0.33 (0.44) 0.19 (0.29) 0.019
Vasopressor dependency index at post-PMX(/mmHg) 0.13 (0.26) 0.14 (0.28) 0.845
PaO2/FIO2 ratio at pre-PMX 210 (234) 199 (206) 0.980
PaO2/FIO2 ratio at post-PMX 254 (181) 172 (156) 0.041
Endotoxin level before the PMX treatment (pg/mL) 15.8 (60.5) 6.1 (23.7) 0.195
Endotoxin level after the PMX treatment (pg/mL) 1.4 (18.2) 0.8 (0.7) 0.267
Suspected causative microorganisms (GNR/GPC/GPR/unknown origin) 24/6/2/10 17/6/0/13 0.428
Median survival time (days) 72 131 0.172
Ventilator-dependent time (days) 13 (33) 7 (42) 0.557
  1. Data are presented as number of cases or median (IQR). IQR interquartile range, MAP mean arterial pressure, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, PMX polymyxin B-immobilized fiber column hemoperfusion, GNR Gram-negative rod, GPC Gram-positive cocci, GPR Gram-positive rods.