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Table 3 Patient characteristics of improvement group and non-improvement group

From: Polymyxin B-immobilized fiber column hemoperfusion mainly helps to constrict peripheral blood vessels in treatment for septic shock

 

Improvement ( n = 42)

Non-improvement ( n = 36)

p value

Sex (male/female)

24/18

26/10

0.237

Age (years)

69 (13)

71 (34)

0.996

APACHE II score

24 (12)

24 (12)

0.980

SOFA score

11 (4)

11 (7)

0.996

MAP at baseline (mmHg)

62 (10)

72 (22)

0.343

Creatinine at baseline (mg/dl)

1.28 (1.72)

1.65 (1.85)

1.000

Lactate level at baseline (mmol/L)

3.2 (5.9)

4.2 (4.9)

0.599

Patients with diabetes mellitus

13

11

1.000

Patients received corticosteroid therapy

8

5

0.762

The times of PMX therapy

1 (1)

1 (1)

0.281

Total PMX treatment time (min)

1598 (2972)

1412 (2254)

0.237

Inotropic score at pre-PMX

24.7 (21.0)

10.3 (18.6)

0.001

Inotropic score at post-PMX

6.8 (15.6)

16.6 (32.8)

0.037

Vasopressor dependency index at pre-PMX (/mmHg)

0.33 (0.44)

0.19 (0.29)

0.019

Vasopressor dependency index at post-PMX(/mmHg)

0.13 (0.26)

0.14 (0.28)

0.845

PaO2/FIO2 ratio at pre-PMX

210 (234)

199 (206)

0.980

PaO2/FIO2 ratio at post-PMX

254 (181)

172 (156)

0.041

Endotoxin level before the PMX treatment (pg/mL)

15.8 (60.5)

6.1 (23.7)

0.195

Endotoxin level after the PMX treatment (pg/mL)

1.4 (18.2)

0.8 (0.7)

0.267

Suspected causative microorganisms (GNR/GPC/GPR/unknown origin)

24/6/2/10

17/6/0/13

0.428

Median survival time (days)

72

131

0.172

Ventilator-dependent time (days)

13 (33)

7 (42)

0.557

  1. Data are presented as number of cases or median (IQR). IQR interquartile range, MAP mean arterial pressure, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, PMX polymyxin B-immobilized fiber column hemoperfusion, GNR Gram-negative rod, GPC Gram-positive cocci, GPR Gram-positive rods.