Table 1 Demographic and clinical characteristics of patients with VAP caused by A. baumannii
Variables | All cases | Survivors | Non-survivors | P value |
|---|---|---|---|---|
( n = 337) | ( n = 174) | ( n = 163) | ||
Male gender, n (%) | 154 (45.7) | 87 (50) | 67 (41) | 0.101 |
Age, mean ± SD | 61.6 ± 18.0 | 60.0 ± 20.0 | 63.5 ± 15.5 | 0.301 |
Comorbidity, n (%) | ||||
Renal diseases | 110 (32.6) | 51 (29.3) | 59 (36.2) | 0.178 |
Cerebrovascular diseases | 92 (27.3) | 51 (29.3) | 41 (25.2) | 0.392 |
Cardiovascular diseases | 94 (27.9) | 49 (28.2) | 45 (27.6) | 0.910 |
COPD | 56 (16.6) | 30 (17.2) | 26 (16.0) | 0.750 |
Diabetes mellitus (DM) | 56 (16.6) | 27 (15.6) | 29 (17.8) | 0.591 |
Immunocompromised hostsa | 64 (19.0) | 23 (13.3) | 41 (25.2) | 0.006 |
Malignancy | 47 (13.9) | 12 (7.0) | 35 (21.5) | <0.001 |
Hematologic diseases | 28 (8.3) | 10 (5.7) | 18 (11.0) | 0.059 |
Hepatic diseases | 28 (8.3) | 14 (8.0) | 14 (8.6) | 0.857 |
VAP onset, n (%) | 0.851 | |||
Early | 38 (11.4) | 20 (11.7) | 18 (11.0) | |
Late | 296 (88.6) | 151 (88.3) | 145 (89.0) | |
CXR: extents of infiltration, n (%) | 0.075 | |||
Single lobe | 300 (89.0) | 160 (92.0) | 140 (85.9) | |
Multi-lobes | 37 (11.0) | 14 (80) | 23 (14.1) | |
CPIS, mean ± SD | 8.2 ± 1.4 | 7.97 ± 1.2 | 8.5 ± 1.5 | 0.002 |
Sepsis status, n (%) | <0.001 | |||
Severe sepsis | 178 (52.8) | 143 (82.2) | 35 (21.5) | |
Septic shock | 159 (47.2) | 31 (17.8) | 128 (78.5) | |
Severity score | <0.001 | |||
SAPS II, mean ± SD | 46.3 ± 14.2 | 39.0 ± 11.2 | 54.0 ± 12.7 | |
SOFA, mean ± SD | 6.7 ± 2.7 | 5.4 ± 2.3 | 8.2 ± 2.3 | <0.001 |
Admission day before VAP onset, median (IQR) | 10 (13) | 10 (9) | 10 (14) | 0.499 |
MV day before VAP onset, median (IQR) | 9 (8) | 9 (7) | 9 (12) | 0.485 |