|
Variables
|
All cases
|
Survivors
|
Non-survivors
|
P
value
|
|---|
|
(
n
= 337)
|
(
n
= 174)
|
(
n
= 163)
|
|---|
|
Male gender, n (%)
|
154 (45.7)
|
87 (50)
|
67 (41)
|
0.101
|
|
Age, mean ± SD
|
61.6 ± 18.0
|
60.0 ± 20.0
|
63.5 ± 15.5
|
0.301
|
|
Comorbidity, n (%)
| | | | |
|
Renal diseases
|
110 (32.6)
|
51 (29.3)
|
59 (36.2)
|
0.178
|
|
Cerebrovascular diseases
|
92 (27.3)
|
51 (29.3)
|
41 (25.2)
|
0.392
|
|
Cardiovascular diseases
|
94 (27.9)
|
49 (28.2)
|
45 (27.6)
|
0.910
|
|
COPD
|
56 (16.6)
|
30 (17.2)
|
26 (16.0)
|
0.750
|
|
Diabetes mellitus (DM)
|
56 (16.6)
|
27 (15.6)
|
29 (17.8)
|
0.591
|
|
Immunocompromised hostsa
|
64 (19.0)
|
23 (13.3)
|
41 (25.2)
|
0.006
|
|
Malignancy
|
47 (13.9)
|
12 (7.0)
|
35 (21.5)
|
<0.001
|
|
Hematologic diseases
|
28 (8.3)
|
10 (5.7)
|
18 (11.0)
|
0.059
|
|
Hepatic diseases
|
28 (8.3)
|
14 (8.0)
|
14 (8.6)
|
0.857
|
|
VAP onset, n (%)
| | | |
0.851
|
|
Early
|
38 (11.4)
|
20 (11.7)
|
18 (11.0)
|
|
Late
|
296 (88.6)
|
151 (88.3)
|
145 (89.0)
|
|
CXR: extents of infiltration, n (%)
| | | |
0.075
|
|
Single lobe
|
300 (89.0)
|
160 (92.0)
|
140 (85.9)
|
|
Multi-lobes
|
37 (11.0)
|
14 (80)
|
23 (14.1)
|
|
CPIS, mean ± SD
|
8.2 ± 1.4
|
7.97 ± 1.2
|
8.5 ± 1.5
|
0.002
|
|
Sepsis status, n (%)
| | | |
<0.001
|
|
Severe sepsis
|
178 (52.8)
|
143 (82.2)
|
35 (21.5)
|
|
Septic shock
|
159 (47.2)
|
31 (17.8)
|
128 (78.5)
|
|
Severity score
| | | |
<0.001
|
|
SAPS II, mean ± SD
|
46.3 ± 14.2
|
39.0 ± 11.2
|
54.0 ± 12.7
|
|
SOFA, mean ± SD
|
6.7 ± 2.7
|
5.4 ± 2.3
|
8.2 ± 2.3
|
<0.001
|
|
Admission day before VAP onset, median (IQR)
|
10 (13)
|
10 (9)
|
10 (14)
|
0.499
|
|
MV day before VAP onset, median (IQR)
|
9 (8)
|
9 (7)
|
9 (12)
|
0.485
|
-
COPD chronic obstructive pulmonary disease, CPIS clinical pulmonary infection score, MV mechanical ventilator, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, IQR interquartile range, CXR chest X-ray, VAP ventilator-associated pneumonia.
-
aImmunocompromised hosts including SLE, HIV/AIDS, and immunosuppressant.
