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Table 1 Demographic and clinical characteristics of patients with VAP caused by A. baumannii

From: Prognostic factors associated with mortality of drug-resistant Acinetobacter baumannii ventilator-associated pneumonia

Variables All cases Survivors Non-survivors P value
( n= 337) ( n= 174) ( n= 163)
Male gender, n (%) 154 (45.7) 87 (50) 67 (41) 0.101
Age, mean ± SD 61.6 ± 18.0 60.0 ± 20.0 63.5 ± 15.5 0.301
Comorbidity, n (%)     
 Renal diseases 110 (32.6) 51 (29.3) 59 (36.2) 0.178
 Cerebrovascular diseases 92 (27.3) 51 (29.3) 41 (25.2) 0.392
 Cardiovascular diseases 94 (27.9) 49 (28.2) 45 (27.6) 0.910
 COPD 56 (16.6) 30 (17.2) 26 (16.0) 0.750
 Diabetes mellitus (DM) 56 (16.6) 27 (15.6) 29 (17.8) 0.591
 Immunocompromised hostsa 64 (19.0) 23 (13.3) 41 (25.2) 0.006
 Malignancy 47 (13.9) 12 (7.0) 35 (21.5) <0.001
 Hematologic diseases 28 (8.3) 10 (5.7) 18 (11.0) 0.059
 Hepatic diseases 28 (8.3) 14 (8.0) 14 (8.6) 0.857
VAP onset, n (%)     0.851
 Early 38 (11.4) 20 (11.7) 18 (11.0)
 Late 296 (88.6) 151 (88.3) 145 (89.0)
CXR: extents of infiltration, n (%)     0.075
 Single lobe 300 (89.0) 160 (92.0) 140 (85.9)
 Multi-lobes 37 (11.0) 14 (80) 23 (14.1)
CPIS, mean ± SD 8.2 ± 1.4 7.97 ± 1.2 8.5 ± 1.5 0.002
Sepsis status, n (%)     <0.001
 Severe sepsis 178 (52.8) 143 (82.2) 35 (21.5)
 Septic shock 159 (47.2) 31 (17.8) 128 (78.5)
Severity score     <0.001
 SAPS II, mean ± SD 46.3 ± 14.2 39.0 ± 11.2 54.0 ± 12.7
 SOFA, mean ± SD 6.7 ± 2.7 5.4 ± 2.3 8.2 ± 2.3 <0.001
Admission day before VAP onset, median (IQR) 10 (13) 10 (9) 10 (14) 0.499
MV day before VAP onset, median (IQR) 9 (8) 9 (7) 9 (12) 0.485
  1. COPD chronic obstructive pulmonary disease, CPIS clinical pulmonary infection score, MV mechanical ventilator, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, IQR interquartile range, CXR chest X-ray, VAP ventilator-associated pneumonia.
  2. aImmunocompromised hosts including SLE, HIV/AIDS, and immunosuppressant.