Figure 1

Comparison of circulating 8-OH-dG, CRP, and lactate levels between surviving and non-surviving septic mice. (a) Circulating 8-OH-dG levels between surviving and non-surviving septic mice. The circulating 8-OH-dG levels in the blood samples collected from surviving mice 72 h after CLP (n = 9) and non-surviving mice at the time of death (CLP = 21) were determined by high-performance liquid chromatography. Data represent means ± standard error of the mean (SEM) of at least six independent experiments. *p < 0.05 vs. the surviving group. (b) Serum C-reactive protein levels between surviving and non-surviving septic mice. Serum C-reactive protein concentrations in the blood samples from surviving mice 72 h after CLP (n = 9) and non-surviving mice at the time of death (CLP = 21) were evaluated. Data represent means ± SEM of at least six independent experiments. (c) Serum lactate levels between surviving and non-surviving septic mice. Serum lactate concentrations in the blood samples prepared from surviving mice 72 h after CLP (n = 9) and non-surviving mice at the time of death (CLP = 21). Data represent means ± SEM of at least six independent experiments. *p < 0.05 vs. the surviving group.