Table 2 The comparison of infectious subgroups
Sepsis (n = 11) | Severe sepsis without shock (n = 12) | Septic shock (n = 24) | p value | |
|---|---|---|---|---|
Age (year) | 70.6 ± 13.7 | 65.2 ± 19.0 | 67.8 ± 15.3 | 0.716 |
Gender, n (%) | 0.058 | |||
Male | 5 (45.5) | 11 (91.7) | 16 (66.7) | |
Female | 6 (54.5) | 1 (8.3) | 8 (33.3) | |
BMI, kg/m2 | 21.6 (18.4,24.1) | 20.6 (20.1,21.7) | 23.9 (20.5,28.8) | 0.090 |
Concomitant disease, n (%) | ||||
Diabetes mellitus | 3 (27.3) | 6 (50.0) | 9 (37.5) | 0.531 |
Hypertension | 5 (45.5) | 3 (25.0) | 12 (50.0) | 0.351 |
CKD | 4 (36.4) | 2 (16.7) | 13 (54.2) | 0.001 |
CPB duration, min | 102.0 ± 129.4 | 187.5 ± 134.8 | 245.6 ± 133.4 | 0.017 |
Aortic cross clamping, min | 69.4 ± 92.4 | 108.8 ± 84.2 | 107.8 ± 111.4 | 0.542 |
Operation time, min | 418.5 ± 136.1 | 540.8 ± 121.7 | 534.5 ± 231.9 | 0.206 |
Blood loss, mL | 802 (398,2489) | 6790 (1364,8324) | 2530 (1227,4961) | 0.019 |
APACHE II | 15.5 ± 6.1 | 16.8 ± 7.6 | 23.5 ± 6.2 | 0.002 |
SOFA | 5.5 ± 1.4 | 5.9 ± 2.9 | 8.2 ± 2.5 | 0.004 |
ICU stay, day | 12.0 (4.0,23.0) | 13.0 (7.3,24.5) | 49.5 (17.8,81) | 0.001 |
Hospital stay, day | 60.9 ± 59.6 | 114.2 ± 85.5 | 124.5 ± 101.0 | 0.152 |
30-Day mortality, n (%) | 0 | 0 | 3 (12.5) | 0.215 |
Hospital mortality, n (%) | 0 | 0 | 22 (91.7) | 0.001 |
MV duration, h | 40.0 (16.0,183.0) | 58.5 (13.5,404.3) | 992.5 (276.3,1559.3) | 0.001 |
CRRT, n (%) | 3 (27.3) | 2 (16.7) | 21 (87.5) | 0.001 |
PMX-DHP, n (%) | 0 | 0 | 17 (70.8) | 0.001 |
ECMO, n (%) | 0 | 1 (8.3) | 12 (50.0) | 0.001 |
DIC, n (%) | 0 | 1 (8.3) | 22 (91.7) | 0.024 |
PCT, ng/mL | 1.37 (0.72,1.85) | 3.16 (0.48,13.24) | 3.68 (1.67,20.96) | 0.024 |
WBC, ×103/μL | 12.40 (9.10,24.20) | 13.30 (9.93,16.93) | 20.40 (13.45,28.6) | 0.060 |
CRP, mg/dL | 12.00 (7.40,18.00) | 13.57 (8.17,18.13) | 17.11 (15.15,30.6) | 0.009 |
Gram positive, n (%) | ||||
MRSA | 0 | 0 | 6 (25.0) | 0.037 |
S. epidermidis | 2 (18.7) | 4 (33.3) | 1 (4.2) | 0.064 |
E. faecalia | 0 | 0 | 3 (12.5) | 0.215 |
C. striatum | 0 | 0 | 3 (12.5) | 0.215 |
Gram negative, n (%) | ||||
S. marcescens | 0 | 2 (16.7) | 2 (8.3) | 0.359 |
P. aeruginosa | 1 (9.1) | 1 (8.3) | 3 (12.5) | 0.913 |
B. cepacia | 1 (9.1) | 1 (8.3) | 1 (4.2) | 0.815 |
K. pneumoniae | 1 (9.1) | 1 (8.3) | 0 | 0.335 |
Candida, n (%) | ||||
C. albicans | 4 (36.4) | 2 (16.7) | 3 (12.5) | 0.242 |
C. glabrata | 0 | 0 | 2 (8.3) | 0.368 |
C. parapsilosis | 0 | 1 (8.3) | 1 (4.2) | 0.613 |
C. tropicalis | 1 (9.1) | 1 (8.3) | 1 (4.2) | 0.815 |