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Table 7 Multiple logistic regression analysis of risk factors affecting serious bleeding AEs

From: Post-marketing surveillance data of thrombomodulin alfa: sub-analysis in patients with sepsis-induced disseminated intravascular coagulation

Item

Odds ratio (95% CI)

p value

Sex (female/male)

0.631

(0.403–0.970)

0.0355

History of bleeding risk, presence

2.899

(1.839–4.504)

< 0.0001

Pre-existing bleeding symptoms, presence

2.983

(1.885–4.655)

< 0.0001

Fibrinogen before TM-α administration

0.997

(0.996–0.999)

< 0.0001

  1. A total of 1,602 DIC patients diagnosed by JAAM DIC criteria were analyzed by multiple logistic regression analysis; AE adverse event, TM-α thrombomodulin alfa.