Figure 5
From: IV injection of polystyrene beads for mouse model of sepsis causes severe glomerular injury
Evaluation of inflammatory reaction. Mice were randomized to polystyrene bead injection (108/kg, 6-μm dia.) (Bead), LPS injection (5 mg/kg) (LPS), polystyrene bead injection (108/kg, 6-μm dia.) 30 min after LPS injection (5 mg/kg) (L + B), or saline injection (5 ml/kg) (Control) and treated as described. Twenty-four or 48 h after injection, serum was obtained and measured. n = 4 in each group. Single asterisk, double asterisks, third asterisks, significantly different from Control at P < 0.05, 0.01, 0.001, respectively. (A) White blood cell count 48 h after injection. (B) Differential count of leukocytes 48 h after injection. (C) Serum IL-6 24 h after injection.