Figure 4
From: IV injection of polystyrene beads for mouse model of sepsis causes severe glomerular injury
Evaluation of kidney function. Mice were randomized to polystyrene bead injection (108/kg, 6-μm dia.) (Bead), LPS injection (5 mg/kg) (LPS), polystyrene bead injection (108/kg, 6-μm dia.) 30 min after LPS injection (5 mg/kg) (L + B), or saline injection (5 ml/kg) (Control) and treated as described. Forty-eight hours after injection, serum was obtained and measured. n = 4 in each group. Double asterisks, triple asterisks, significantly different from Control at P < 0.01, 0.001, respectively. Single number sign, triple number signs, significantly different between LPS and L + B at P < 0.05, 0.001, respectively. (A) Serum BUN 48 h after injection. (B) Serum creatinine 48 h after injection. (C) Serum cystatin C 48 h after injection.