Figure 3
From: IV injection of polystyrene beads for mouse model of sepsis causes severe glomerular injury
Analysis of histology. In the sections obtained from Figure 2, the percentage of injured glomeruli in the kidney, infiltration of neutrophils into red pulp per unit area, and percentage of white pulp area of the spleen were analyzed. Control (n = 4), Bead (n = 4), LPS (n = 4), L + B (n = 5). Single asterisk, triple asterisks, significantly different from Control at P < 0.05, 0.001, respectively. Triple number signs, significantly different between LPS and L + B at P < 0.001. (A) Percentage of injured glomeruli in the kidney. Injured and uninjured glomeruli in each kidney section of Figure 1 were counted, and the percentages of injured glomeruli are presented. (B) Infiltration of neutrophils into red pulp per unit area. In spleen sections of Figure 1, neutrophils in red pulp were counted and presented as per unit area. (C) Percentage of white pulp area of spleen. In the spleen sections of Figure 1, areas of white and red were measured, and the percentage of the white area is presented.