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Figure 1 | Journal of Intensive Care

Figure 1

From: IV injection of polystyrene beads for mouse model of sepsis causes severe glomerular injury

Figure 1

Survival study. Both 3- and 6-μm diameter polystyrene beads were investigated. Mice were randomized to polystyrene bead injection (106, 108, or 109/kg) (Bead), LPS injection (5 mg/kg) (LPS), polystyrene bead injection (106, 108, or 109/kg) 30 min after LPS injection (5 mg/kg) (L + B), or saline injection (5 ml/kg) (Control) and treated as described. The animals were observed in cages, and the status of dead or alive was recorded every 24 h for 10 days. n = 10 in each group. Asterisk, significantly different from Control at P < 0.05. Number sign, significantly different from 109/kg within the L + B groups of 6-μm diameter polystyrene beads. (A) Survival curve of study (polystyrene beads 3-μm diameter, 108/kg). (B) Survival curve of study (polystyrene beads 6-μm diameter, 108/kg). (C) Survival curve of study (polystyrene beads 6-μm diameter, 106/kg). (D) Survival curve of study (polystyrene beads 6-μm diameter, 109/kg).

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