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Table 2 Laboratory tests for DIC

From: Diagnosis and treatment of disseminated intravascular coagulation (DIC) according to four DIC guidelines

  Abnormality in DIC Other cause for the abnormality Adequate type of DIC
PT Prolongation Liver dysfunction, vitamin K deficiency OF, BL, MB
FDP, D-dimer Elevation Venous thromboembolism, operation BL, NS, OF
Fibrinogen Reduction Liver dysfunction BL, MB
Platelet count Reduction Bone marrow disorders OF, MB, BL, NS
AT/PC Reduction Liver dysfunction, capillary leak syndrome OF
SF/TAT Elevation Venous thromboembolism, operation OF, NS, BL, MS
TM Elevation Renal dysfunction, organ failure OF
VWFpp, PAI-I Elevation Organ failure OF
ADATMTS13 Reduction Liver dysfunction, thrombotic microangiopathy OF
APTT Biphasic waveform Infection OF
PPIC Elevation Venous thromboembolism, operation BL, MB
  1. PT, prothrombin time; FDP, fibrinogen and fibrin degradation products; SF, soluble fibrin; AT, antithrombin; PC, protein C; TAT, thrombin AT complex; VWFpp, von Willebrand factor propeptide; PAI-I, plasminogen activator inhibitor-I; APTT, activated partial thromboplastin time; PPIC, plasmin-plasmin inhibitor complex; OF, organ failure type of DIC; BL, bleeding type of DIC; MB, massive bleeding type of DIC; NS, non-symptomatic type of DIC.