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Table 1 Incidence of hypothermia (body temperature <35.5°C) and associated outcomes in patients with severe sepsis

From: Body temperature abnormalities in non-neurological critically ill patients: a review of the literature

Hypothermia (<35.5°C), %

Mortality (%)

<35.5°C

≥35.5°C

Methylprednisolone Severe Sepsis Study [16] (n = 382), 9%

62

26

Veterans Administration Systemic Sepsis Cooperative Study of Glucocorticoid Therapy [47] (n = 223), 10%

57

28

Ibuprofen Sepsis Study [19] (n = 453), 9.6%

70

35

NORASEPT II Study (tissue factor pathway inhibitor) [46], (n = 930, septic shock), 21%

59

34

JAAM Sepsis Registry [49] (n = 624), 15.9%

40.4

17.7

  1. JAAM Japanese Association for Acute Medicine.