Table 3 Proteins required for the translocation of Pseudomonas aeruginosa Exo effectors
Protein | PA number | Size (kDa) | Amino acids | Homolog in Yersinia | Features | Localization | Role |
|---|---|---|---|---|---|---|---|
PcrG | PA1705 | 11 | 98 | LcrG (56%) | Binds to PcrV | Bacterial cytosol | Negative regulator |
PcrV | PA1706 | 32.3 | 294 | LcrV (57%) | Cap, Pore | Bacterial Surface | Translocational pore |
PcrH | PA1707 | 18.4 | 167 | LcrH/SycD (76%) | Binds to PopB and PopD | Bacterial cytosol | Chaperone for PopB and PopD |
PopB | PA1708 | 40.1 | 390 | YopB (60%–61%) | Pore | On eukaryotic cell membrane | Translocational pore |
PopD | PA1699 | 31.3 | 295 | YopD (59%–60%) | Pore | On eukaryotic cell membrane | Translocational pore |