Table 1 The major toxic exoproducts of Pseudomonas aeruginosa
Exoproducts | Locus ID, PA number | Effect on host | Secretion type | Regulation system |
|---|---|---|---|---|
Exotoxin A | toxA, PA1148 | Antiphagocytic, cytotoxic | Type II | (LasR-LasI quorum sensing) |
Exoenzyme S | exoS, PA3841 | Antiphagocytic, cytotoxic | Type III | ExsA-activated type III system |
Elastase (LasA, LasB) | lasA, PA1871 | Elastolytic activity | Type II | LasR-LasI quorum sensing |
lasB, PA3724 | ||||
Alkaline proteinase | aprA, PA1249 | Â | Type I | LasR-LasI quorum sensing |
Phospholipase C | plcH, PA0844 | Disturbance of membrane lipid metabolism | Type II | Inorganic phosphate |
| Â | plcN, PA3319 | Â | Â | Â |