No drug | Epinephrine | P value | |
---|---|---|---|
(n = 315) | (n = 318) | ||
Age (year) | 71 ± 17 | 71 ± 16 | 0.887 |
Gender, male (%) | 194 (62) | 228 (72) | 0.009 |
Bystander performed CPR, n (%) | 141 (45) | 140 (44) | 0.873 |
VF/VT as initial rhythm at starting CPR by EMTs, n (%) | 83 (26) | 90 (28) | 0.594 |
Asystole, n (%) | 138 (44) | 151 (48) | 0.228 |
Pulseless electrical activity, n (%) | 94 (30) | 77 (24) | |
VT, n (%) | 2 (0.6) | 1 (0.3) | |
VF, n (%) | 81 (26) | 89 (28) | |
Advanced life support by a physician in the ambulance, n (%) | 165 (52) | 167 (53) | 1.000 |
From call receipt to ambulance stop (min) | 6.3 ± 2.6 | 6.6 ± 2.8 | 0.141 |
From call receipt to start CPR by EMTs (min) | 8.1 ± 3.8 | 8.1 ± 3.1 | 0.784 |
From witnessed cardiac arrest to start CPR by EMTs (min) | 9.5 ± 7.6 | 9.7 ± 7.8 | 0.701 |
From the start of CPR by EMTs to departure from the scene (min) | 13.3 ± 4.8 | 14.7 ± 4.3 | <0.001 |
From the start of CPR by EMTs to arrival at the hospital (min) | 25.2 ± 8.5 | 29.1 ± 8.4 | <0.001 |
CPR time (min) | 21.1 ± 9.6 | 26.9 ± 9.0 | <0.001 |
From witnessed cardiac arrest to the first epinephrine administration (min) | - | 22.5 ± 8.4 | - |
From start CPR by EMTs to the first epinephrine administration (min) | - | 13.3 ± 5.9 | - |
Frequency of epinephrine administration until arrival at the hospital | - | 2.5 ± 1.5 | - |
Outcome | |||
ROSC before arrival at the hospital, n (%) | 78 (25) | 73 (23) | 0.641 |
From start CPR by EMTs to ROSC (min) | 11.9 ± 8.1 | 19.6 ± 6.9 | <0.001 |
Admission to the intensive care units, n (%) | 126 (40) | 124 (39) | 0.808 |
Survival 7 days after the cardiac arrest, n (%) | 86 (27) | 65 (20) | 0.050 |
Survival 30 days after the cardiac arrest, n (%) | 76 (24) | 53 (17) | 0.023 |
Favorable neurological state 30 days after, n (%) | 54 (17) | 25 (8) | <0.001 |
Good performance | 44 (14) | 18 (6) | |
Moderate disability | 10 (3) | 7 (2) | |
Severe disability | 4 (1) | 5 (2) | 0.009 |
Vagitative | 18 (6) | 23 (7) | |
Dead | 239 (76) | 265 (93) |