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  1. Review

    Update on pediatric sepsis: a review

    Sepsis is one of the leading causes of mortality among children worldwide. Unfortunately, however, reliable evidence was insufficient in pediatric sepsis and many aspects in clinical practice actually depend o...

    Tatsuya Kawasaki

    Journal of Intensive Care 2017 5:47

    Published on: 20 July 2017

  2. Review

    Current status of pediatric transplantation in Japan

    Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50–60 brain-dead donor organ transplants performed annually in Japan, ...

    Nao Nishimura, Mureo Kasahara, Kenji Ishikura and Satoshi Nakagawa

    Journal of Intensive Care 2017 5:48

    Published on: 20 July 2017

  3. Research

    Impact of a sepsis bundle in wards of a tertiary hospital

    Sepsis is a prevalent disease worldwide and still exhibits high rates of mortality. In the last years, many interventions aiming a positive impact on sepsis evolution have been studied. One of the main is the ...

    F. Teles, W. G. Rodrigues, M. G. T. C. Alves, C. F. T. Albuquerque, S. M. O. Bastos, M. F. A. Mota, E. S. Mota and F. J. L. Silva

    Journal of Intensive Care 2017 5:45

    Published on: 18 July 2017

  4. Research

    AN69ST membranes adsorb nafamostat mesylate and affect the management of anticoagulant therapy: a retrospective study

    In Japan, nafamostat mesylate (NM) is frequently used as an anticoagulant during continuous renal replacement therapy (CRRT). The dialyzer membrane AN69ST has been reported to adsorb NM and affect the manageme...

    Takahiro Hirayama, Nobuyuki Nosaka, Yasumasa Okawa, Soichiro Ushio, Yoshihisa Kitamura, Toshiaki Sendo, Toyomu Ugawa and Atsunori Nakao

    Journal of Intensive Care 2017 5:46

    Published on: 18 July 2017

  5. Research

    Factors associated with increased pancreatic enzymes in septic patients: a prospective study

    The perfusion of splanchnic organs is deeply altered in patients with septic shock. The aim of the study is to identify the predictive factors of septic shock-induced increase of serum lipase and amylase and t...

    Anis Chaari, Karim Abdel Hakim, Nevine Rashed, Kamel Bousselmi, Vipin Kauts, Mahmoud Etman and William Francis Casey

    Journal of Intensive Care 2017 5:44

    Published on: 14 July 2017

  6. Research

    Unexpected intensive care transfer of admitted patients with severe sepsis

    Patients with severe sepsis generally respond well to initial therapy administered in the emergency department (ED), but a subset later decompensate and require unexpected transfer to the intensive care unit (...

    Gabriel Wardi, Arvin R. Wali, Julian Villar, Vaishal Tolia, Christian Tomaszewski, Christian Sloane, Peter Fedullo, Jeremy R. Beitler, Matthew Nolan, Daniel Lasoff and Rebecca E. Sell

    Journal of Intensive Care 2017 5:43

    Published on: 12 July 2017

  7. Research

    Usefulness of plasminogen activator inhibitor-1 as a predictive marker of mortality in sepsis

    Sepsis is one of the most significant causes of mortality in intensive care units. It indicates crosstalk between inflammation and coagulation. In this study, we aimed to identify prognostic markers among seps...

    Kota Hoshino, Taisuke Kitamura, Yoshihiko Nakamura, Yuhei Irie, Norihiko Matsumoto, Yasumasa Kawano and Hiroyasu Ishikura

    Journal of Intensive Care 2017 5:42

    Published on: 11 July 2017

  8. Case report

    Argatroban for an alternative anticoagulant in HIT during ECMO

    Extracorporeal membrane oxygenation (ECMO) have become more frequently used in daily ICU practice, heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication while on extracorporeal mem...

    Alain Rougé, Felix Pelen, Michel Durand and Carole Schwebel

    Journal of Intensive Care 2017 5:39

    Published on: 28 June 2017

  9. Review

    The practice of tracheostomy decannulation—a systematic review

    Decannulation is an essential step towards liberating tracheostomized patients from mechanical ventilation. However, despite its perceived importance, there is no universally accepted protocol for this vital t...

    Ratender Kumar Singh, Sai Saran and Arvind K. Baronia

    Journal of Intensive Care 2017 5:38

    Published on: 20 June 2017

  10. Research

    Physiological impact of high-flow nasal cannula therapy on postextubation acute respiratory failure after pediatric cardiac surgery: a prospective observational study

    Reintubation after pediatric cardiac surgery is associated with a high rate of mortality. Therefore, adequate respiratory support for postextubation acute respiratory failure (ARF) is important. However, littl...

    Naohiro Shioji, Tatsuo Iwasaki, Tomoyuki Kanazawa, Kazuyoshi Shimizu, Tomohiko Suemori, Kentaro Sugimoto, Yasutoshi Kuroe and Hiroshi Morimatsu

    Journal of Intensive Care 2017 5:35

    Published on: 6 June 2017

  11. Letter to the Editor

    The application of anticoagulant therapy to sepsis

    Since the withdrawal of recombinant-activated protein C, the anticoagulant therapy for sepsis was taken no notice. For instance, the international sepsis guidelines did not share a space for this therapy. Howe...

    Jecko Thachil and Toshiaki Iba

    Journal of Intensive Care 2017 5:32

    Published on: 30 May 2017

  12. Research

    Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium

    Patients in intensive care units (ICU) are often diagnosed with postoperative delirium; the duration of which has a relevant negative impact on various clinical outcomes. Recent research found a potentially im...

    Mira John, E. Wesley Ely, Dorothee Halfkann, Julika Schoen, Beate Sedemund-Adib, Stefan Klotz, Finn Radtke, Sebastian Stehr and Michael Hueppe

    Journal of Intensive Care 2017 5:29

    Published on: 26 May 2017

  13. Research

    Association between recurrence of acute kidney injury and mortality in intensive care unit patients with severe sepsis

    Acute kidney injury (AKI) occurs in more than half critically ill patients admitted in intensive care units (ICU) and increases the mortality risk. The main cause of AKI in ICU is sepsis. AKI severity and othe...

    Emilio Rodrigo, Borja Suberviola, Miguel Santibáñez, Lara Belmar, Álvaro Castellanos, Milagros Heras, Juan Carlos Rodríguez-Borregán, Angel Luis Martín de Francisco and Claudio Ronco

    Journal of Intensive Care 2017 5:28

    Published on: 22 May 2017

  14. Research

    Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation: an observational cohort study

    Intracranial hemorrhage (ICH) is a recognized complication of adults treated with extracorporeal membrane oxygenation (ECMO) and is associated with increased morbidity and mortality. However, the predictors of...

    Alexander Fletcher Sandersjöö, Jiri Bartek Jr., Eric Peter Thelin, Anders Eriksson, Adrian Elmi-Terander, Mikael Broman and Bo-Michael Bellander

    Journal of Intensive Care 2017 5:27

    Published on: 22 May 2017

  15. Research

    C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients

    Endothelin 1 (ET-1) is a strong vasoconstrictor, which is involved in inflammation and reduced tissue perfusion. C-terminal proendothelin-1 (CT-proET-1) is the stable circulating precursor protein of ET-1. We ...

    Lukas Buendgens, Eray Yagmur, Jan Bruensing, Ulf Herbers, Christer Baeck, Christian Trautwein, Alexander Koch and Frank Tacke

    Journal of Intensive Care 2017 5:25

    Published on: 20 March 2017

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