Articles
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Citation: Journal of Intensive Care 2023 11:33
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The influence of steroid type on outcomes in patients with acute respiratory distress syndrome
Recent systematic reviews and meta-analyses have suggested that low-dose steroids are effective in the treatment of acute respiratory distress syndrome (ARDS). Recent guidelines recommend the use of low-dose s...
Citation: Journal of Intensive Care 2023 11:32 -
Prevention and management of critical care complications in cardiogenic shock: a narrative review
Cardiogenic shock (CS) is a common cause of morbidity and mortality in cardiac intensive care units (CICUs), even in the contemporary era.
Citation: Journal of Intensive Care 2023 11:31 -
Alteration of circulating redox balance in coronavirus disease-19-induced acute respiratory distress syndrome
Mechanisms underpinning ARDS induced by COVID-19 are mostly immune-mediated, but need to be completely clarified. This study aimed to investigate redox balance in COVID-19 patients with ARDS, trying to recogni...
Citation: Journal of Intensive Care 2023 11:30 -
Different definitions of feeding intolerance and their associations with outcomes of critically ill adults receiving enteral nutrition: a systematic review and meta-analysis
A unified clinical definition of feeding intolerance (FI) is urged for better management of enteral nutrition (EN) in critically ill patients. We aimed to identify optimum clinical FI definitions based on repo...
Citation: Journal of Intensive Care 2023 11:29 -
Correlation between tissue Doppler-derived left ventricular systolic velocity (S’) and left ventricle ejection fraction in sepsis and septic shock: a retrospective cohort study
Tissue Doppler-derived left ventricular systolic velocity (mitral S’) has shown excellent correlation to left ventricular ejection fraction (LVEF) in non-critically patients. However, their correlation in sept...
Citation: Journal of Intensive Care 2023 11:28 -
Association of body mass index with mortality of sepsis or septic shock: an updated meta-analysis
The effects of body mass index (BMI) on mortality of sepsis remain unknown, since previous meta-analyses have reported conflicting results. Several observational studies published recently have provided new ev...
Citation: Journal of Intensive Care 2023 11:27 -
Organ dysfunction, injury, and failure in cardiogenic shock
Cardiogenic shock (CS) is caused by primary cardiac dysfunction and induced by various and heterogeneous diseases (e.g., acute impairment of cardiac performance, or acute or chronic impairment of cardiac perfo...
Citation: Journal of Intensive Care 2023 11:26 -
Stomach position evaluated using computed tomography is related to successful post-pyloric enteral feeding tube placement in critically ill patients: a retrospective observational study
Post-pyloric enteral feeding reduces respiratory complications and shortens the duration of mechanical ventilation. Blind placement of post-pyloric enteral feeding tubes (EFT) in patients with critical illness...
Citation: Journal of Intensive Care 2023 11:25 -
The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation
The International Society on Thrombosis and Haemostasis (ISTH) released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001. Since then, DIC has been understood as the end-stage cons...
Citation: Journal of Intensive Care 2023 11:24 -
Post-intensive care syndrome (PICS): recent updates
An increasing number of patients are surviving critical illness, but some experience new or worsening long-lasting impairments in physical, cognitive and/or mental health, commonly known as post-intensive care...
Citation: Journal of Intensive Care 2023 11:23 -
Fundamental concepts and the latest evidence for esophageal pressure monitoring
Transpulmonary pressure is an essential physiologic concept as it reflects the true pressure across the alveoli, and is a more precise marker for lung stress. To calculate transpulmonary pressure, one needs an...
Citation: Journal of Intensive Care 2023 11:22 -
Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial
Long-term outcomes of patients treated with helmet noninvasive ventilation (NIV) are unknown: safety concerns regarding the risk of patient self-inflicted lung injury and delayed intubation exist when NIV is a...
Citation: Journal of Intensive Care 2023 11:21 -
The impact of a preoperative nurse-led orientation program on postoperative delirium after cardiovascular surgery: a retrospective single-center observational study
Postoperative delirium in intensive care is common and associated with mortality, cognitive impairment, prolonged hospital stays and high costs. We evaluate whether a nurse-led orientation program could reduce...
Citation: Journal of Intensive Care 2023 11:20 -
Intensivist coverage and critically ill COVID-19 patient outcomes: a population-based cohort study
Trained intensivist staffing improves survival outcomes in critically ill patients at intensive care units. However, the impact on outcomes of critically ill patients with coronavirus disease 2019 has not yet ...
Citation: Journal of Intensive Care 2023 11:19 -
Comparison of the efficacy and comfort of high-flow nasal cannula with different initial flow settings in patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis
High-flow nasal cannula (HFNC) has been proven effective in improving patients with acute hypoxemic respiratory failure (AHRF), but a discussion of its use for initial flow settings still need to be provided. ...
Citation: Journal of Intensive Care 2023 11:18 -
Association of blood viscosity and device-free days among hospitalized patients with COVID-19
Increased estimated whole blood viscosity (eWBV) predicts higher mortality in patients hospitalized for coronavirus disease 2019 (COVID-19). This study assesses whether eWBV is an early predictor of non-fatal ...
Citation: Journal of Intensive Care 2023 11:17 -
Association between the timing of ICU admission and mortality in patients with hospital-onset sepsis: a nationwide prospective cohort study
Based on sparse evidence, the current Surviving Sepsis Campaign guideline suggests that critically ill patients with sepsis be admitted to the intensive care unit (ICU) within 6 h. However, limited ICU bed ava...
Citation: Journal of Intensive Care 2023 11:16 -
Potential of cell-free hemoglobin and haptoglobin as prognostic markers in patients with ARDS and treatment with veno-venous ECMO
Hemolysis is associated with increased mortality in patients with sepsis, ARDS, or therapy with extracorporeal membrane oxygenation (ECMO). To quantify a critical threshold of hemolysis in patients with ARDS a...
Citation: Journal of Intensive Care 2023 11:15 -
Mechanical power and 30-day mortality in mechanically ventilated, critically ill patients with and without Coronavirus Disease-2019: a hospital registry study
Previous studies linked a high intensity of ventilation, measured as mechanical power, to mortality in patients suffering from “classic” ARDS. By contrast, mechanically ventilated patients with a diagnosis of ...
Citation: Journal of Intensive Care 2023 11:14 -
Onset timing and duration of augmented renal clearance in a mixed intensive care unit
Augmented renal clearance (ARC) is associated with lower blood plasma concentrations of renally excreted drugs; however, its time course is unknown. The current study aimed to determine the onset timing/durati...
Citation: Journal of Intensive Care 2023 11:13 -
Prehospital tranexamic acid for trauma victims
The public enquiry into the mass casualty incident at the Manchester Arena in the UK in which 23 people died and over 1000 were injured, identified the need for timely intramuscular administration of tranexami...
Citation: Journal of Intensive Care 2023 11:12 -
Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study
Acute kidney injury (AKI) is a frequent syndrome in the intensive care unit (ICU). AKI patients with kidney function recovery have better short-term and long-term prognoses compared with those with non-recover...
Citation: Journal of Intensive Care 2023 11:11 -
Guideline-based management of acute respiratory failure and acute respiratory distress syndrome
Acute respiratory failure (ARF) is defined by acute and progressive hypoxemia caused by various cardiorespiratory or systemic diseases in previously healthy patients. Among ARF, acute respiratory distress synd...
Citation: Journal of Intensive Care 2023 11:10 -
An evaluation of the impact of the implementation of the Tele-ICU: a retrospective observational study
The telemedicine intensive care unit (Tele-ICU) is defined as a system in which intensive care professionals remotely provide care to critically ill patients and support the on-site staff in the intensive care...
Citation: Journal of Intensive Care 2023 11:9 -
Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study
The development of disseminated intravascular coagulation (DIC) in patients with sepsis has been repeatedly confirmed as a factor associated with poor prognosis. Anticoagulant therapy has been expected to impr...
Citation: Journal of Intensive Care 2023 11:8 -
The time cost of physiologically ineffective intravenous fluids in the emergency department: an observational pilot study employing wearable Doppler ultrasound
Little data exist on the time spent by emergency department (ED) personnel providing intravenous (IV) fluid to ‘responsive’ versus ‘unresponsive’ patients.
Citation: Journal of Intensive Care 2023 11:7 -
Descriptive statistics and risk factor analysis of children with community-acquired septic shock
Children with community-acquired septic shock can rapidly deteriorate and die in acute-care hospitals. This study aimed to describe the mortality, timing, and risk factors in children with community-acquired s...
Citation: Journal of Intensive Care 2023 11:6 -
Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review
A growing body of evidence supports the use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) refractory to maximal medical therapy. ARDS may develop in a prop...
Citation: Journal of Intensive Care 2023 11:5 -
Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study
Current guidelines recommend systemic thrombolysis as the first-line reperfusion treatment for patients with high-risk pulmonary embolism (PE) who present with cardiogenic shock but do not require venoarterial...
Citation: Journal of Intensive Care 2023 11:4 -
Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study
sCD59, as a soluble form of CD59, is observed in multiple types of body fluids and correlated with the cell damage after ischemia/reperfusion injury. This study aims to observe the dynamic changes of serum sCD...
Citation: Journal of Intensive Care 2023 11:3 -
Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group
A substantial number of sepsis patients require specialized care, including multidisciplinary care, close monitoring, and artificial organ support in the intensive care unit (ICU). However, the efficacy of ICU...
Citation: Journal of Intensive Care 2023 11:2 -
Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study
Tigecycline has in vitro bacteriostatic activity against a broad spectrum of bacteria, including carbapenem-resistant Gram-negative bacteria (CR-GNB). However, the role of tigecycline in treatment of nosocomia...
Citation: Journal of Intensive Care 2023 11:1 -
Timing of tracheostomy and patient outcomes in critically ill patients requiring extracorporeal membrane oxygenation: a single-center retrospective observational study
Extracorporeal membrane oxygenation (ECMO) is an integral method of life support in critically ill patients with severe cardiopulmonary failure; however, such patients generally require prolonged mechanical ve...
Citation: Journal of Intensive Care 2022 10:56 -
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study
Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory set...
Citation: Journal of Intensive Care 2022 10:55 -
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study
The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. The objective was to determine how delirium subtypes are associated with hospital morta...
Citation: Journal of Intensive Care 2022 10:54 -
Comment on: Post‑resuscitation diastolic blood pressure is a prognostic factor for outcomes of cardiac arrest patients
Citation: Journal of Intensive Care 2022 10:53 -
Intensive care unit versus high-dependency care unit admission on mortality in patients with septic shock: let’s think to the survival chain concept for septic shock
Citation: Journal of Intensive Care 2022 10:52 -
Impact of the COVID-19 pandemic on critical care utilization in Japan: a nationwide inpatient database study
The coronavirus disease 2019 (COVID-19) pandemic has disrupted critical care services worldwide. Examining how critical care systems responded to the COVID-19 pandemic on a national level will be useful in set...
Citation: Journal of Intensive Care 2022 10:51 -
The revised recommendation for administering vitamin C in septic patients: the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020
Given the available clinical evidence through the literature search when the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 was being created, we suggested administering v...
Citation: Journal of Intensive Care 2022 10:50 -
Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study
The appropriate duration of antibiotic treatment in patients with bacterial sepsis remains unclear. The purpose of this study was to evaluate the association of a shorter course of antibiotics on 28-day mortal...
Citation: Journal of Intensive Care 2022 10:49 -
The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study
Fontan surgery with cardiopulmonary bypass (CPB) causes tremendous systemic stress and inflammatory responses, affecting postoperative organ function, morbidity, and mortality. Although this reaction triggers ...
Citation: Journal of Intensive Care 2022 10:48 -
Correction: Intensive care unit versus high-dependency care unit admission on mortality in patients with septic shock: a retrospective cohort study using Japanese claims data
Citation: Journal of Intensive Care 2022 10:47 -
Prone positioning in ARDS patients supported with VV ECMO, what we should explore?
Acute respiratory distress syndrome (ARDS), a prevalent cause of admittance to intensive care units, is associated with high mortality. Prone positioning has been proven to improve the outcomes of moderate to ...
Citation: Journal of Intensive Care 2022 10:46 -
Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury
There is little known about the contribution of microRNAs (miRNAs) in the recovery from acute kidney injury (AKI). This study aimed to discover and validate miRNA profiles for predicting renal recovery from se...
Citation: Journal of Intensive Care 2022 10:45 -
Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients
Up to 11% of critically ill patients with sepsis have an unknown source, where the pathogen and site of infection are unclear. The aim of this scoping review is to document currently reported diagnostic criter...
Citation: Journal of Intensive Care 2022 10:44 -
Benefit with preventive noninvasive ventilation in subgroups of patients at high-risk for reintubation: a post hoc analysis
High-flow nasal cannula (HFNC) was shown to be non-inferior to noninvasive ventilation (NIV) for preventing reintubation in a general population of high-risk patients. However, some subgroups of high-risk pati...
Citation: Journal of Intensive Care 2022 10:43 -
Difference between 5A score and the HOPE score
Recently, a letter to the editor was published to comment on the 5A score which is the prediction model for accidental hypothermia patients comparing the HOPE score. In this letter, we responded to the comment...
Citation: Journal of Intensive Care 2022 10:42 -
Association between ICU admission during off-hours and in-hospital mortality: a multicenter registry in Japan
The effect of ICU admission time on patient outcomes has been shown to be controversial in several studies from a number of countries. The imbalance between ICU staffing and medical resources during off-hours ...
Citation: Journal of Intensive Care 2022 10:41 -
Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients
Diaphragm fiber atrophy has been evidenced after short periods of mechanical ventilation (MV) and related to critical illness-associated diaphragm weakness. Atrophy is described as a decrease in diaphragm fibe...
Citation: Journal of Intensive Care 2022 10:40
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- ISSN: 2052-0492 (electronic)